Generalized anxiety disorder

Researchers are testing whether a personalized form of brain stimulation can ease symptoms in people with anxiety disorders that have not improved with standard treatments. The approach uses a device to deliver rapid magnetic pulses to specific brain circuits, guided by each pers…

This trial is testing the long-term safety and tolerability of an investigational drug called SEP-363856 (ulotaront) in adults with generalized anxiety disorder (GAD). Participants who completed a previous phase 3 study will take the drug daily for 26 weeks. The study will monito…

Researchers are studying whether a broad-spectrum oral tincture containing CBD, CBN, and CBG changes anxiety symptoms in adults with generalized anxiety disorder. About 60 participants will take the tincture under the tongue or by mouth roughly every 12 hours for 8 weeks, with fo…

This study tests whether a single session of low-intensity focused ultrasound (LIFU) can safely reduce chronic pain and anxiety symptoms. Ten adults with either generalized anxiety disorder or chronic pain will receive multiple ultrasound pulses in one visit and be followed for s…

This study investigates whether a single session of whole-body hyperthermia (using an infrared sauna) can quickly improve symptoms of depression and anxiety. Researchers will measure brain activity, inflammation, and mood changes in four groups: healthy postpartum women, postpart…

This study looks at whether taking a daily probiotic powder can help adults with overactive bladder (OAB) and anxiety. About 218 people will take either probiotics or a placebo for 12 weeks, while everyone also learns bladder training. The main goals are to see if probiotics redu…

This study tests a program that combines yoga with cognitive behavioral therapy (CBT) to help people with Generalized Anxiety Disorder. Researchers will measure changes in anxiety levels, psychological resilience, and daily functioning in 64 adults. The goal is to see if this min…

This study tests a non-invasive brain stimulation method called cTBS for treating generalized anxiety disorder. 60 adults will receive either real or sham stimulation to two brain areas over 7 days. Researchers will measure changes in anxiety symptoms and brain activity using MRI…

This study looks at whether electroacupuncture (a type of acupuncture with mild electric pulses) can reduce anxiety in people with Generalized Anxiety Disorder. About 123 adults will be split into three groups: real electroacupuncture, fake electroacupuncture, or a waiting list. …

This study will test a smartphone app called CONEMO in over 12,000 adults visiting primary care clinics. The app uses cognitive behavioral therapy techniques to help reduce symptoms of depression, anxiety, and insomnia. Participants will use the app on their own phones or tablets…

This study tests whether very short (4 or 8 sessions) psychological treatments can reduce symptoms of anxiety, depression, and stress-related physical complaints. About 184 adults with mild to moderate symptoms will be randomly assigned to group or individual therapy, or a relaxa…

This study explores how financial insecurity—such as trouble paying for housing, food, or healthcare—affects the mental health of university students and whether it keeps them from seeking help. Researchers will conduct in-depth interviews with 30 students from two French univers…

This study will follow 45,000 university students over three years to understand how financial struggles, housing issues, and loneliness affect their mental health and whether they seek help. Participants will fill out questionnaires about their well-being and life circumstances.…

This early-stage study looks at how the drug buagafuran (AF-5) behaves in people with liver impairment compared to those with normal liver function. Twenty-four adults will receive a single 30 mg dose, and researchers will measure drug levels in the blood and monitor safety. The …