FIBROSIS

This study is testing the safety of a new inhaled drug, mosliciguat, when added to an existing inhaled medication (treprostinil) for people with pulmonary hypertension caused by scarred lungs (interstitial lung disease). The goal is to see if the two-drug combination is safe and …

This small pilot study is testing whether giving copper supplements to people with advanced liver scarring (cirrhosis) is safe and can improve their health. It will involve 30 adult patients who have cirrhosis and low copper levels. Researchers want to see if raising copper level…

This study is testing if two common medications—pentoxifylline with vitamin E or pravastatin—can prevent or reduce painful swelling and scarring (lymphedema and fibrosis) that often occurs after radiation treatment for head and neck cancer. The trial will enroll about 295 adults …

This study aims to find out if certain medications can help treat or prevent lymphedema (swelling) and fibrosis (scarring) caused by radiation therapy in people who have survived head and neck cancer. Researchers will compare different drugs to see which works best at reducing th…

This study aims to understand if different types of HIV medications affect the development or severity of fatty liver disease in people living with HIV. Researchers will follow 200 Chinese patients to see if starting with or switching between two common drug classes leads to diff…

This study aims to understand if weakness in the main breathing muscle (the diaphragm) is common in people with lung diseases like asthma, COPD, fibrosis, or pulmonary hypertension, and if it can predict future health problems. Researchers will measure muscle strength, lung funct…