FIBROSIS

This study is testing the safety of a new inhaled drug, mosliciguat, when added to an existing inhaled medication (treprostinil) for people with pulmonary hypertension caused by scarred lungs (interstitial lung disease). It will enroll about 20 participants who are already using …

This small pilot study is testing whether giving copper supplements to people with advanced liver scarring (cirrhosis) is safe and can improve their health. It will involve 30 adult patients who have cirrhosis and low copper levels. Researchers want to see if raising copper level…

This study is testing if two common medications—pentoxifylline with vitamin E or pravastatin—can prevent or reduce painful swelling and scarring (lymphedema and fibrosis) that often occurs after radiation treatment for head and neck cancer. The trial will enroll about 295 adults …

This study aims to find out if certain medications can help treat or prevent lymphedema (swelling) and fibrosis (scarring) caused by radiation therapy in people who have survived head and neck cancer. Researchers will compare different drugs to see which works best at reducing th…

This study aims to understand if weakness in the main breathing muscle (the diaphragm) is common in people with lung diseases like asthma, COPD, fibrosis, or pulmonary hypertension, and if it can predict future health problems. Researchers will measure muscle strength, lung funct…

This study aims to understand if different types of HIV medication affect the development of fatty liver disease. Researchers will follow 200 Chinese patients with HIV to see if starting or switching certain drugs leads to more severe liver fat buildup or scarring. The goal is to…