ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC)
Clinical trials for ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC) explained in plain language.
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New surgical wrap could slash leak risk in esophageal cancer patients
Disease control Not yet recruitingThis study tests a new surgical technique for people with esophageal cancer. The method uses a special dye to check blood flow to the stomach, then wraps the surgical connection with a piece of the patient's own stomach lining to prevent leaks. About 73 adults will take part to s…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC)
Phase: PHASE2 • Sponsor: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University • Aim: Disease control
Last updated May 26, 2026 07:02 UTC
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Immunotherapy combo shows promise in esophageal cancer trial
Disease control Not yet recruitingThis study tests whether adding the immunotherapy drug toripalimab to chemotherapy before surgery can improve outcomes for people with a type of esophageal cancer that can be surgically removed. About 390 adults with locally advanced esophageal squamous cell carcinoma will be ran…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC)
Phase: PHASE3 • Sponsor: Tang-Du Hospital • Aim: Disease control
Last updated May 26, 2026 07:00 UTC
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New protocol aims to seal deadly fistulas in esophageal cancer patients
Disease control Not yet recruitingThis study tests a standardized treatment plan for esophageal fistula, a severe complication in advanced esophageal cancer that can cause life-threatening infections and malnutrition. The plan includes sealing the fistula with stents, targeted antibiotics, nutritional support, an…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC)
Sponsor: Peking University Cancer Hospital & Institute • Aim: Disease control
Last updated May 26, 2026 06:59 UTC
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New hope for tough esophageal cancers: Low-Dose radiation boosts immunotherapy
Disease control Not yet recruitingThis study tests a combination of the immunotherapy drug toripalimab, chemotherapy, and low-dose radiation in people with esophageal cancer that did not shrink after initial treatment. About 48 adults will receive the combo before surgery to see if it can kill more cancer cells. …
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC)
Phase: PHASE2 • Sponsor: Tianjin Medical University Cancer Institute and Hospital • Aim: Disease control
Last updated May 26, 2026 06:52 UTC
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New combo therapy aims to shrink esophageal tumors before surgery
Disease control Not yet recruitingThis study tests a new approach for people with a type of esophageal cancer that can be surgically removed. Before surgery, participants receive a short course of radiation, followed by three cycles of an immunotherapy drug (serplulimab) plus standard chemotherapy. The goal is to…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC)
Phase: PHASE2 • Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology • Aim: Disease control
Last updated May 26, 2026 06:50 UTC
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New hope for esophageal cancer: immunotherapy after chemoradiation may keep tumors at bay
Disease control Not yet recruitingThis phase 3 trial tests whether the immunotherapy drug toripalimab can help people with advanced esophageal cancer that hasn't grown after initial treatment. About 340 adults will be randomly assigned to receive toripalimab or just observation. The goal is to see if the drug del…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC)
Phase: PHASE3 • Sponsor: Tianjin Medical University Cancer Institute and Hospital • Aim: Disease control
Last updated May 22, 2026 13:53 UTC
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New study uses High-Tech tests to predict esophageal cancer outcomes
Knowledge-focused Not yet recruitingThis study follows 255 people with esophageal cancer to see how the disease changes over time. Researchers use blood tests, scans, and tissue samples to find patterns that might predict if treatment is working or if cancer returns. The goal is to improve how doctors personalize c…
Matched conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC)
Sponsor: Peking University Cancer Hospital & Institute • Aim: Knowledge-focused
Last updated May 26, 2026 06:47 UTC