ER POSITIVE BREAST CANCER
Clinical trials for ER POSITIVE BREAST CANCER explained in plain language.
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New pill targets Hard-to-Treat cancers with AKT1 mutation
Disease control OngoingThis early-stage study tests an experimental pill, ATV-1601, in people with advanced solid tumors (including certain breast, ovarian, and prostate cancers) that have a specific AKT1 gene mutation. The main goals are to check the drug's safety, find the best dose, and see how the …
Matched conditions: ER POSITIVE BREAST CANCER
Phase: PHASE1 • Sponsor: Atavistik Bio, Inc • Aim: Disease control
Last updated May 26, 2026 04:15 UTC
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Promising breast cancer drug trial pulled before starting
Disease control TerminatedThis study was designed to see if the drug trastuzumab deruxtecan works better than standard CDK4/6 inhibitors for people with a specific type of advanced breast cancer (ER-positive, HER2-low, non-luminal A). It was planned for adults with metastatic disease. However, the trial w…
Matched conditions: ER POSITIVE BREAST CANCER
Phase: PHASE3 • Sponsor: Danish Breast Cancer Cooperative Group • Aim: Disease control
Last updated May 26, 2026 04:15 UTC
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Blood test may help doctors switch cancer treatment sooner
Knowledge-focused OngoingThis study looks at whether a simple blood test that tracks cancer DNA (ctDNA) can help doctors decide when to switch treatments for people with stage IV breast cancer. The goal is to see if changing therapy earlier, based on the blood test, can keep the cancer under control long…
Matched conditions: ER POSITIVE BREAST CANCER
Phase: PHASE2 • Sponsor: University of Miami • Aim: Knowledge-focused
Last updated May 26, 2026 04:13 UTC
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New study explores how letrozole affects breast cancer tumors before surgery
Knowledge-focused OngoingThis study looks at how the drug letrozole works in postmenopausal women with early-stage, hormone-sensitive breast cancer before they have surgery. About 178 participants will take letrozole for 4 to 24 weeks, and researchers will compare tumor samples taken before and after tre…
Matched conditions: ER POSITIVE BREAST CANCER
Phase: PHASE2 • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Knowledge-focused
Last updated May 18, 2026 12:07 UTC