EOSINOPHILIC ESOPHAGITIS

This study is testing whether a drug called tezepelumab, given as an injection, can help control eosinophilic esophagitis (EoE). About 368 adults and teens with EoE will receive either the drug or a placebo for one year to see if it reduces inflammation in the esophagus and impro…

This study is testing whether a diet that eliminates specific foods identified by a person's immune system tests works better than a fake diet to control Eosinophilic Esophagitis (EoE). One hundred participants, aged 16-80 with active EoE, will be randomly assigned to follow eith…

This study is testing whether children with a chronic inflammatory condition of the esophagus (Eosinophilic Esophagitis) can stay in remission using half their usual steroid dose. It aims to see if this lower dose is enough to control the disease while potentially reducing the ri…

This study is testing how well an already FDA-approved drug, dupilumab, works for people with a severe form of Eosinophilic Esophagitis (EoE) that causes dangerous narrowing of the esophagus. All 30 participants will receive weekly dupilumab injections under the skin for one year…

This study aims to check the long-term safety of an investigational drug called CC-93538 for people with eosinophilic esophagitis (EoE), a chronic inflammatory condition of the esophagus. It is open to about 368 adults and adolescents who have already taken the drug in earlier, r…

This program provided expanded access to the experimental medication APT-1011 for people with eosinophilic esophagitis (EoE) who couldn't participate in regular clinical trials or had exhausted other treatment options. Patients received a 120-day supply of the oral dissolving tab…

This study aimed to test a new swallowable capsule with a tiny camera to take pictures inside the esophagus. The goal was to see if it could diagnose conditions like eosinophilic esophagitis (EoE) as well as the current standard method, which requires sedation and multiple biopsi…

This study is testing a new swallowable camera capsule to see if it can take clear pictures of the esophagus. Researchers want to know if the device is comfortable to use and produces useful images. The study includes 96 people, both healthy volunteers and those with or suspected…

This study aimed to understand the long-term safety of a common treatment for eosinophilic esophagitis (EoE) in children. Researchers planned to compare bone density and growth rates over one year in children aged 5-12 taking swallowed steroids for EoE against similar children no…

This study aims to understand the biological and genetic reasons why some people develop food allergies and why many children outgrow them. Researchers will collect blood samples from about 5,300 participants, including people with food allergies and healthy family members, to an…