EOSINOPHILIC ESOPHAGITIS

This study tests whether dupilumab, an FDA-approved drug, can help people with severe eosinophilic esophagitis (EoE) who have narrowing of the esophagus. 23 participants will receive weekly injections for one year. The goal is to see if the drug reduces inflammation and improves …

This study tests an experimental drug called tezepelumab in 368 adults and teens (ages 12-80) with eosinophilic esophagitis, a condition where allergy cells build up in the esophagus and make swallowing painful or difficult. Participants receive either the drug or a placebo as a …

This program provides early access to APT-1011 (a swallowed steroid tablet) for people aged 12 and older with eosinophilic esophagitis (EoE) who cannot join other studies or have tried all available treatments. The goal is to control the disease until the drug becomes commerciall…

This study looks at whether children with eosinophilic esophagitis (a condition that makes swallowing difficult) can safely cut their steroid dose in half and still stay in remission. About 50 kids who are already in remission on full-dose steroids will be switched to a lower dos…

This study tests a new, less invasive device called the Esophageal String Test (EST) to diagnose and monitor eosinophilic esophagitis (EoE), a rare inflammatory condition of the esophagus. Instead of a traditional biopsy, patients swallow a small string that collects samples to m…

This study aimed to see if a special camera capsule could diagnose Eosinophilic Esophagitis and Barrett Esophagus by taking pictures of the esophagus, instead of using a standard biopsy. The study was withdrawn before any participants were enrolled, so no results are available. I…

This study tests a special camera capsule that people swallow to take detailed pictures of the esophagus. It includes healthy volunteers and people with eosinophilic esophagitis (EoE). The goal is to see if the capsule works well and is comfortable enough to use in the future.

This study is looking at the biological and genetic reasons why some people develop food allergies and others outgrow them. Researchers will collect blood samples from up to 5,300 people, including those with food allergies, their family members, and healthy volunteers. The goal …

This study planned to check if swallowed corticosteroids, a common treatment for eosinophilic esophagitis (EoE) in children, could harm bone density or slow growth. It was designed for kids aged 5-12 with EoE who were starting this medication. However, the study was withdrawn bef…