Can half the steroid dose keep Kids' esophagitis at bay?
NCT ID NCT05309590
First seen Mar 20, 2026 · Last updated Jun 19, 2026 · Updated 11 times
Summary
This study looks at whether children with eosinophilic esophagitis (EoE) can safely cut their steroid dose in half and still stay in remission. The 50 participants have already achieved remission on a full dose of topical steroids like fluticasone or budesonide. Researchers will track how many maintain remission on the lower dose over time.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Ann & Robert H Lurie Childjren's Hospital of Chicago
Chicago, Illinois, 60611, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
topical steroids (fluticasone and budesonide)
What this could lead to
If successful, this could show that a lower steroid dose is enough to keep the disease under control, reducing potential side effects from long-term use.
What could go wrong
This is a small pilot study with only 50 children, so results may not apply to everyone. Lowering the dose might cause the disease to come back in some patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.