ENDOTHELIAL DYSFUNCTION

This study is testing whether a natural plant compound called fisetin can improve blood vessel function and reduce artery stiffness in adults aged 65 and older. Researchers will give fisetin in short, repeated cycles to 70 participants to see if it helps clear out 'worn-out' cell…

This study is testing whether eating wild blueberries daily can help lower blood pressure and improve artery function in middle-aged and older adults with mildly elevated blood pressure. Researchers are enrolling 58 men and postmenopausal women aged 45-70 to measure changes in bl…

This study is testing if a medication called dulaglutide can improve the health of tiny blood vessels in the muscles of adults with type 1 diabetes. Researchers believe better blood flow might help the body use insulin more effectively. The trial is currently suspended and was co…

This study aims to better understand why people experience chest pain and reduced blood flow to the heart despite having no major blockages in their arteries. Researchers will enroll 500 participants with this condition to perform detailed heart tests and track their health over …

This was an add-on study to a larger trial testing whether inhaling nitric oxide gas during and after heart surgery helps protect patients' blood vessels. It aimed to understand how the gas works, specifically looking at patients with existing blood vessel problems who needed ver…

This study aimed to see if a blood test could detect and predict future blockages in the small blood vessels of the heart in people who have had a heart transplant. It planned to enroll 88 adults who were at least 3 years past their transplant to compare blood test results with s…

This was an add-on study to a larger trial testing nitric oxide gas in heart surgery patients. It aimed to understand the biological mechanisms—specifically how nitric oxide affects oxidative stress levels in the blood—that might explain why the gas could help reduce post-surgery…