EMPHYSEMA

This study is testing a new clinic designed to find and treat muscle loss (sarcopenia) in people with COPD. About 80 adults who have been hospitalized for COPD will join. The clinic uses CT scans to check muscle mass and offers a team approach with a lung doctor, pharmacist, and …

This study is testing the long-term safety and effectiveness of the Spiration Valve System for people with severe emphysema, a lung condition that makes breathing difficult. About 150 adults with low collateral ventilation (meaning the valves can work properly) will receive the v…

This study tests a permanent implant called the Apreo BREATHE Airway Scaffold in up to 250 adults with COPD and emphysema who still feel short of breath despite standard treatments. The implant is placed in the airways to release trapped air and keep them open. Researchers will c…

This study tests a new device called an implantable artificial bronchus (IAB) for people with severe emphysema or COPD. The goal is to see if the device can improve lung function and make breathing easier. About 60 adults will take part, and the main results will be checked 90 da…

This study tests a new device called the IAB 50 Flex, an implant designed to help people with severe emphysema or COPD breathe easier. About 20 adults will receive the implant at two hospitals. The main goal is to check for serious side effects within 90 days.

This study explores how a minimally invasive lung valve treatment changes leg muscle function in people with severe emphysema. Researchers will measure muscle energy use and take small tissue samples before and 6 months after the procedure. The goal is to understand why patients …

This study is building a large registry of 3,000 people with emphysema or COPD, plus a control group without lung disease. Researchers will collect DNA, lung function tests, and medical history to better understand the disease and identify candidates for future treatment trials. …