DRY EYE DISEASE

This study tested a new eye drop called AR-15512 in 80 adults with dry eye disease. The goal was to see if the drops could improve the health of the eye's surface, specifically by increasing the number of goblet cells that help keep the eye moist. Participants used the drops for …

This study tested a medicated eye drop called cenegermin (Oxervate) in 85 adults with severe dry eye caused by Sjogren's syndrome, who were already using another eye drop (cyclosporine). The goal was to see if cenegermin could increase tear production and reduce dry eye symptoms …

This study tested an experimental eye drop called INV-102 in 84 adults with moderate dry eye disease. The goal was to check safety and see if it reduces eye dryness. Participants used the drops for two weeks, and researchers measured changes in dryness symptoms.

This study tested a new eye drop (AR-15512) for dry eye disease in 55 adults. The goal was to see how many people had eye-related side effects compared to a standard artificial tear (REFRESH® Classic). Results help understand the safety of this new drop for future use.

This study tested the safety of an eye drop called reproxalap in 757 adults with dry eye disease. Participants used the drops for up to 12 months, and researchers watched for serious side effects like vision changes or increased eye pressure. The goal was to see if the treatment …

This study tested a new eye drop called reproxalap (0.25%) in 116 adults with dry eye disease. The goal was to see if it reduces eye discomfort better than a placebo drop. Participants rated their discomfort over 100 minutes in a dry environment. The trial is complete and results…

This study tested an eye drop called SI-614 in 232 people with dry eye disease. The goal was to see if it reduces eye damage and discomfort better than a placebo. Participants used the drops for about a month, and researchers measured changes in eye staining and daily symptoms.

This study tested an experimental eye drop called SHJ002 in 85 adults with dry eye disease. The goal was to see if it safely reduces eye damage and improves symptoms compared to a placebo. Participants used the drops for several weeks, and doctors measured changes in corneal stai…

This study tested a new lubricating eye drop in 188 adults with mild to moderate dry eye disease. Participants used the drops and reported their symptoms after 30 days. The results showed that the drops helped reduce eye discomfort, with no major safety concerns.

This study tested whether eye drops made from a patient's own blood (autologous serum) can relieve severe dry eye symptoms better than standard artificial tears. 46 adults with severe dry eye disease tried both diluted (20%) and undiluted (100%) serum drops, as well as artificial…

This study tested a medicated eyelid wipe called IVW-1001 in 150 adults with dry eye disease. The goal was to see if it safely improves tear production and eases symptoms like irritation. Participants used the wipe or a placebo for a period, and doctors measured changes in tear a…

This study tested whether using the Systane iLux system, a device that applies heat and pressure to the eyelids, could improve dry eye symptoms in 30 people scheduled for cataract surgery. Participants received the treatment before surgery, and researchers measured changes in tea…

This study tested a new eye drop containing a natural protein (rhNGF) to see if it can safely relieve symptoms of dry eye disease. 317 adults with moderate-to-severe dry eye used the drops or a placebo for 4 weeks. The goal was to measure improvements in eye discomfort and tear p…

This study tested a new eye drop called AR-15512 in 81 adults with dry eye disease. The goal was to see if it could quickly increase tear production, measured by tear meniscus height using a special camera. Results showed a positive change from baseline at 3 minutes after use, su…

This study tested a nasal spray called OC-01 (varenicline) in 50 adults with dry eye disease. The goal was to see if it improves tear film quality and stability compared to a placebo spray. Participants used the spray and had their tears measured at a single visit.

This study tested an eye drop called reproxalap in 421 adults with dry eye disease. Participants used the drops for up to 6 weeks to see if it reduced eye discomfort compared to a placebo. The goal was to ease symptoms, not cure the condition.

This study tested three different ways to use an eyelid wipe (IVW-1001) for people with dry eye disease. Thirty adults took part to see how safe and effective each method was. The main goal was to measure changes in tear production and vision.