DISORDERS OF CONSCIOUSNESS

This early study tests whether gentle electrical stimulation deep inside the brain can help people with long-term disorders of consciousness, such as after a severe injury or stroke. Only 2 participants will receive the treatment to check if it is safe and might improve awareness…

This study looks at whether natural eye blinking patterns can help doctors tell the difference between two states of consciousness after severe brain injury: unresponsive wakefulness and a minimally conscious state. Researchers will track blinking rate, strength, and timing in 70…

This study explores whether measuring brain activity during a gentle rectal balloon stretch can help doctors tell the difference between patients who are minimally conscious and those who are unresponsive. Researchers will record EEGs from 45 adults with disorders of consciousnes…

This study tests a new, non-invasive brain stimulation method called theta-burst patterned temporal interference stimulation (tTIs) to see if it can improve awareness in people with disorders of consciousness, like vegetative or minimally conscious states. About 136 participants …

This study tests a safe, non-invasive technique called transcutaneous auricular vagus nerve stimulation (taVNS) in 20 people with disorders of consciousness after severe brain injury. Participants receive two 20-minute ear stimulation sessions daily for 10 days. The goal is to se…

This study investigates whether patients with disorders of consciousness (like coma or minimally conscious state) can form and recall memories. Researchers will use EEG and skin sensors to detect brain and body responses to memory tasks, without requiring any communication from t…

This study explores whether ultrasound, a low-cost and widely available tool, can help doctors better understand and treat people with disorders of consciousness (DOC), such as coma or a minimally conscious state. Researchers will use brain ultrasound to measure brain activity an…