DIABETIC NEPHROPATHIES

This study tests a new drug called WAL0921 in 96 adults with kidney diseases that cause protein in the urine, including diabetic kidney disease and rare conditions like FSGS. Participants receive either the drug or a placebo as an IV infusion every two weeks for 14 weeks, then ar…

This study tests a new oral solution called ACE Reno in 300 adults with chronic kidney disease from various causes like diabetes or high blood pressure. The goal is to see if taking it four times daily for 12 weeks can reduce protein in the urine and help keep kidneys working lon…

This study tests whether formoterol, a drug typically used for asthma, can help people with diabetic kidney disease. About 120 adults with type 2 diabetes and moderate kidney damage will be randomly assigned to receive either formoterol plus their usual care or usual care alone. …

This study tests whether the drug sotagliflozin can slow kidney function loss in 150 people with type 1 diabetes and moderate to severe kidney disease. Participants will take either the drug or a placebo daily for 3 years, while following a plan to prevent a serious side effect c…

This study looks at kidney tissue from adults with diabetic kidney disease who are already scheduled for a kidney biopsy or surgery as part of their regular care. Researchers want to understand how SGLT2 inhibitors, a type of diabetes medicine, change the kidney's molecular finge…

This study looks at 300 people with type 2 diabetes who have high levels of protein in their urine, a sign of kidney trouble. Researchers will take small kidney samples (biopsies) and analyze blood, urine, and genetic data to find patterns that help diagnose diabetic kidney disea…

This study is for adults with diabetes who need a kidney biopsy as part of their regular care. Researchers will collect and study kidney tissue, blood, urine, and genetic material from 400 participants. The goal is to find out why some people's kidneys decline quickly while other…