DIABETIC MACULAR EDEMA

This study tests a small, refillable implant placed in the eye that slowly releases medicine to treat diabetic macular edema (DME), a leading cause of vision loss in people with diabetes. About 634 adults with DME will either get the implant refilled every 24 weeks or receive sta…

This early-phase trial tests whether an oral drug called Kamuvudine-9 (K9) is safe and can improve vision in people with diabetic macular edema (DME), a diabetes complication that causes vision loss. About 10 adults with diabetes and DME will receive either K9 or a placebo pill. …

This study tests a new medicine called EYP-1901 against a standard treatment (aflibercept) for people with diabetic macular edema, a condition that causes vision loss in people with diabetes. About 240 participants will receive either the new drug or the standard one, and researc…

This early-stage study tests a new medicine (RO7823653) given as an eye injection, alone or with another drug (faricimab), in people with diabetic macular edema (DME) — a condition that causes vision loss. The main goal is to check safety and how the drug behaves in the body. Abo…

This study compares two ways of using laser treatment for proliferative diabetic retinopathy, a leading cause of blindness in working-age adults. Researchers will give 40 participants either a single laser session or multiple sessions to see which is safer and works better. The g…

This study tests a new medicine called EYP-1901 against a standard treatment (aflibercept) for people with diabetic macular edema, a condition that causes blurry vision due to diabetes. About 240 adults will receive either the new drug or the standard one, and researchers will ch…

This early-stage study tests a new drug called OCU200 for people with diabetic macular edema, a condition where fluid builds up in the center of the retina and blurs vision. The main goal is to check safety and side effects, while also measuring how well the drug improves eyesigh…

This early-stage trial tests an oral drug called MS-553 in 45 people with diabetic macular edema, a condition where diabetes causes fluid buildup in the eye's center, blurring vision. Participants take the drug daily for 8 weeks to check its safety and whether it reduces swelling…

This study tests whether levosulpiride, a drug already used for other conditions, can safely improve vision and reduce retinal swelling in people with diabetic retinopathy and diabetic macular edema. About 120 adults aged 40-69 with mild to moderate eye damage will receive either…

This study tests a new medicine called AVT29 against an existing drug, Eylea HD, for people with diabetic macular edema (DME), a condition that causes vision loss in people with diabetes. About 256 adults will receive either AVT29 or Eylea HD to see if AVT29 works just as well at…

This study looks at 150 people with diabetic macular edema (DME) to see if certain markers in the blood and eye scans can predict how well they respond to two common treatments: anti-VEGF injections or a dexamethasone implant. Participants will be divided into groups based on the…

This study is collecting information from 850 people with wet age-related macular degeneration or diabetic macular edema who are being treated with faricimab. Researchers want to see how well the drug works in real-world settings, how it is used, and its safety over two years. Th…