Dengue

This pilot study tested whether giving the Qdenga dengue vaccine into the skin (intradermal) works as well as the standard shot under the skin. 29 healthy Thai adults who had never received a dengue vaccine took part. Researchers measured antibody and T-cell levels at day 0, 30, …

This study tested a new dengue vaccine called V181 against an existing one (Butantan-DV) in 1,364 healthy adults aged 18 to 50 in Brazil. The goal was to see if V181 is as safe and triggers a similar immune response. Results showed V181 was safe and produced comparable antibody l…

This study tested whether an extract from papaya leaves (CPLE) can help people with dengue fever. 250 adults with confirmed dengue were given either CPLE capsules or a placebo for 5 days. The main goals were to see if the extract could raise platelet counts and reduce the risk of…

This study tested whether a drug called fenretinide (ISLA101) can prevent or reduce dengue symptoms. Fifteen healthy adults were given either the drug or a placebo before or after being exposed to a weakened dengue virus. Researchers measured virus levels and immune responses ove…

Researchers in Senegal are testing a new way to care for children under 15 who come to primary health clinics with fever or diarrhea. The strategy combines rapid tests for malaria, dengue, and strep A with a digital tool that suggests treatment based on symptoms and test results.…

Dengue fever is common in Burkina Faso, but primary health clinics often rely only on malaria rapid tests when a child arrives with fever. Researchers are testing a digital module that walks health workers through the country's dengue management guideline and pairs it with dengue…

This study tested whether sending health tips via WhatsApp could help families in Colombia prevent dengue, Zika, and chikungunya. About 900 households were split into three groups: one got WhatsApp messages plus community support, one got community support only, and one got routi…

This study tested whether spraying insecticide on indoor walls (Targeted Indoor Residual Spraying) can prevent diseases spread by Aedes mosquitoes, like dengue, chikungunya, and Zika. Over 4,400 children aged 2 to 15 in Merida, Mexico took part. Researchers tracked how many got s…

Dengue has become a recurring illness on Reunion Island, and repeat infections tend to be more severe. Researchers are following 258 adults and children who arrive at two island hospitals with confirmed or suspected dengue, collecting blood samples and health questionnaires over …

This study looked at how people's immune systems react to proteins in mosquito saliva after being bitten. Researchers exposed 147 healthy adults in Thailand to lab-grown mosquitoes that can carry malaria or dengue. The goal was to find markers in the blood that show how much expo…

This pilot study looked for dengue virus in the sperm of 10 men with active dengue infection. Researchers collected semen, urine, and blood samples over 90 days to see if the virus is present and where it hides. The goal is to understand if the virus can be in sperm and whether s…