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Dengue virus found in sperm? tiny study investigates

NCT ID NCT03612609

Knowledge-focused Sponsor: University Hospital, Toulouse Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study looked for dengue virus in the sperm of 10 men with active dengue infection. Researchers collected semen, urine, and blood samples over 90 days to see if the virus is present and where it hides. The goal is to understand if the virus can be in sperm and whether standard sperm processing can remove it, which could help guide safety advice for men recovering from dengue.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors give better advice to men recovering from dengue about risks of sexual transmission and safety during fertility treatments.
What could go wrong
This is a very small pilot study with only 10 men, so findings may not apply to everyone. It only looks for the virus in sperm, not whether it can actually spread through sex.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

10 people

The number who actually took part.

Started

Feb 2019

Finished

Aug 2019

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient male aged 18 to 45 years * Patient in acute phase of dengue virus infection and with clinical criteria (date of onset of known clinical signs) which if thet aren't specific can be highly evocative in an epidemic zone. For example: Fever, asthenia, rash, arthritis/arthralgia, myalgia, headache, conjunctivitis. * Detection of the dengue virus genome by reverse transcriptase polymerase chain reaction in the blood or urine * Patient who can move to the laboratory for samples * Patient having given his free and informed consent and having signed the consent * Patient affiliated with a social security scheme or equivalent Exclusion Criteria: * Patient with an ejaculation disorder or who cannot sperm collection or with a sperm volume abnormal (\<1,5 ml). * Patient under guardianship or under trusteeship * Patient already included in a research protocol

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Conditions

The condition(s) this trial relates to.

dengue disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dengue

Contacts and locations

Locations

  • Hôpital Saint-Pierre

    Saint-Pierre, 97448, Reunion

More trials for these conditions

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