CUTANEOUS SQUAMOUS CELL CARCINOMA

This study is testing whether a drug called ivonescimab can help control advanced cutaneous squamous cell carcinoma, a type of skin cancer. Researchers will give the drug to 24 patients whose cancer cannot be removed by surgery or has spread. The main goals are to see if the drug…

This study is testing an experimental treatment called RP1 for people who have had an organ or bone marrow transplant and now have advanced skin cancer. RP1 is a modified cold sore virus that is injected directly into tumors to try to destroy them and boost the body's immune resp…

This study is testing whether adding a special heat treatment to standard palliative radiotherapy helps control advanced cancers that cannot be cured by surgery. It will involve about 60 patients with certain advanced head, neck, skin, or breast cancers. The goal is to see if the…

This is an early-stage safety study for a new drug called ANK-101, which is injected directly into tumors. It aims to find a safe dose for people with advanced solid cancers that have stopped responding to standard treatments. The study will test the drug alone in different types…

This is an early-stage study to find a safe dose of an experimental therapy called MQ710 for people with advanced solid tumors that have returned, spread, or stopped responding to standard treatments. The therapy is a modified virus designed to be injected directly into tumors. R…

This study is testing a personalized treatment for people with advanced forms of skin cancer (cutaneous squamous cell carcinoma or Merkel cell carcinoma) that have come back after standard immunotherapy. Doctors take a patient's own immune cells from a tumor, grow large numbers o…

This study is testing whether giving two immunotherapy drugs before surgery can better shrink advanced skin cancer tumors and help prevent the cancer from coming back. It will involve 20 adults with a type of skin cancer called cutaneous squamous cell carcinoma that is advanced b…

This study is testing whether a 3D ultrasound scan of removed skin cancer tissue can accurately measure how close the cancer cells are to the edges of the removed sample. Researchers will compare the ultrasound measurements to the standard laboratory analysis (histopathology) per…

This study aims to find out which of the current skin cancer staging systems best predicts which patients are at higher risk of their cancer returning or spreading. Researchers will look at the medical records of 1,500 people with a common type of skin cancer from two UK clinics.…

This study is testing a new predictive tool to see if it can accurately forecast which patients with melanoma and other cancers will respond to immunotherapy treatments. It will enroll 1,000 patients who are eligible for standard immunotherapy. The goal is to see if this tool can…

This study is testing a blood test to see if it can find leftover cancer cells after surgery or track how well immunotherapy is working for people with a type of skin cancer called cutaneous squamous cell carcinoma. Researchers will collect blood samples from 60 participants over…