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New drug ivonescimab tested for tough cancers

NCT ID NCT06567314

First seen Jan 10, 2026 · Last updated Jun 19, 2026 · Updated 27 times

Summary

This phase 2 trial is testing a drug called ivonescimab in 24 people with advanced cutaneous squamous cell carcinoma (a type of skin cancer) or castration-resistant prostate cancer. The goal is to see if the drug can help control the cancer and to check for side effects. Participants take the drug by mouth, and the study is currently recruiting.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ivonescimab (a drug given by mouth)

What this could lead to

If it works, this could point toward a new treatment option for advanced skin cancer and a hard-to-treat type of prostate cancer.

What could go wrong

This is a small, early-phase trial with only 24 participants, so results may not apply to everyone. The drug may cause side effects or not work as hoped.

Conditions

The condition(s) this trial relates to.

skin squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.