CROHNS DISEASE

This study looks at the long-term safety of a drug called guselkumab in children who have Crohn's disease, ulcerative colitis, or juvenile psoriatic arthritis. About 196 kids who already completed a previous study and benefited from the drug will continue treatment. The main goal…

This study tests a new treatment called TRX103 for people with moderate to severe Crohn's disease that hasn't improved with other treatments. The goal is to see if TRX103 is safe and can reduce gut inflammation. About 39 adults aged 18 to 65 will receive a single infusion of TRX1…

This study looks at whether microplastics in the body can cause or worsen gut inflammation, especially in people with Crohn's disease. Researchers will measure microplastics in stool samples from pregnant women, their babies, and family members. The goal is to understand how envi…

This study looks at whether using bowel ultrasound instead of colonoscopy or CT scans can reduce the carbon footprint of diagnosing and monitoring ulcerative colitis and Crohn's disease. Researchers will measure electricity, water, and waste from each method. 200 adults undergoin…

This study includes about 50 adults with Crohn's disease who have a permanent ileostomy. Researchers will review routine endoscopy videos and interview participants to create new tools that measure inflammation and symptoms. The goal is to help include this group in future clinic…

This study looks at how often people with Crohn's disease, ulcerative colitis, an ileostomy, or bile acid diarrhea have low magnesium levels. Magnesium is important for muscles, nerves, and heart health, but standard blood tests may miss a deficiency. Researchers will compare dif…