Coronary arterial disease (CAD)

Researchers are studying how heart arteries change after a blocked vessel is opened with a paclitaxel drug-coated balloon instead of a metal stent. The balloon delivers a drug to the artery wall and then is removed, leaving no permanent implant. About 150 adults who had this proc…

This trial tests whether a specialized scoring balloon, called Naviscore, can better prepare calcified coronary arteries before placing a drug-eluting stent. Hardened plaques often prevent stents from expanding fully, raising risks of re-narrowing or clots. About 200 adults with …

This study tests advanced CT scans to find dangerous blockages in heart arteries without needing to insert a tube into the heart. About 142 adults with moderate blockages will get two types of CT scans, and results will be compared to the standard invasive test. The goal is to se…

Researchers are testing whether nurse-led lessons delivered through virtual reality or a tablet help people with coronary artery disease understand their heart risks and take their antiplatelet medicines as prescribed. The trial enrolls 54 adults aged 18 to 65 who have coronary a…

This study will check if new risk models can better predict blood clots and bleeding in 5000 adults with coronary heart disease. Participants will be followed for one year to see how well the models work. The goal is to help doctors choose safer, more personalized treatments.