CONGENITAL DIAPHRAGMATIC HERNIA

This study tests a procedure called FETO, where a tiny balloon is placed in the windpipe of a fetus with severe congenital diaphragmatic hernia (CDH). The balloon blocks the airway temporarily, which helps the lungs grow larger before birth. The goal is to improve the baby's chan…

This study tests a procedure called FETO for babies with a severe diaphragmatic hernia, where organs move into the chest and harm lung growth. A tiny balloon is placed in the baby's windpipe while still in the womb to help the lungs grow. The study involves 10 pregnant women and …

This study is testing a procedure called FETO for babies with a severe form of left congenital diaphragmatic hernia, where the diaphragm has a hole and the liver is in the chest. The procedure involves placing a small balloon in the baby's windpipe to help the lungs grow before b…

This study looks at whether keeping the umbilical cord intact while helping a newborn breathe (instead of clamping it right away) improves heart and lung function in full-term babies born with a rare hole in the diaphragm called congenital diaphragmatic hernia (CDH). About 180 ba…

This study looks at whether placing a temporary balloon in the windpipe of unborn babies with severe congenital diaphragmatic hernia (CDH) can help their lungs develop and reduce dangerous high blood pressure in the lungs after birth. Researchers will compare 40 babies who get th…

This study tests a procedure called FETO for unborn babies with a severe form of left congenital diaphragmatic hernia (CDH), where the diaphragm has a hole and the lungs are underdeveloped. The procedure involves placing a tiny balloon in the baby's windpipe to block fluid flow, …

This study looks at whether not using inhaled nitric oxide (iNO) right after birth helps babies with congenital diaphragmatic hernia (CDH). About 600 newborns will be involved. The goal is to see if avoiding iNO reduces the need for a heart-lung machine or death, and if it saves …

This study tests a fetal surgery called FETO (fetoscopic endoluminal tracheal occlusion) in pregnant women carrying babies with severe congenital diaphragmatic hernia (CDH). The goal is to see if temporarily blocking the baby's windpipe helps the lungs grow larger and improves su…

This study tests a procedure called FETO for babies diagnosed with a severe form of congenital diaphragmatic hernia (CDH), where organs move into the chest and crowd the lungs. Doctors place a tiny balloon in the baby's windpipe while still in the womb to help the lungs grow. The…

This study looks at a surgery called FETO, done while the baby is still in the womb, to treat a severe birth defect where the diaphragm muscle has a hole. The goal is to see if FETO helps more babies survive after birth and have fewer health problems compared to standard care. Ab…

This study tests a procedure called FETO for fetuses with severe congenital diaphragmatic hernia (CDH), where the lungs are too small. Doctors place a balloon in the fetus's windpipe to encourage lung growth, then remove it before birth. The trial will enroll 20 pregnant people t…

This study looks at why teenagers who had surgery for a diaphragmatic hernia right after birth may or may not take part in sports and physical activities. Researchers will use surveys and interviews with 20 teens and their parents to find out what helps or hinders their activity.…

This study looks at how hard children with muscle or lung problems have to work to breathe. Researchers will use a small tube to measure breathing effort in 550 kids at Necker Hospital. The goal is to better understand these conditions and improve care.

This study aims to find the genes that cause congenital diaphragmatic hernia (CDH), a serious birth defect. Researchers will collect DNA from 3000 people with CDH or a family history of it, along with their families. By identifying genetic patterns, they hope to better understand…

This study looks at two natural amino acids, arginine and ADMA, in newborns who have abdominal surgery within their first five days of life. Researchers want to see if the balance of these amino acids can help predict how quickly babies recover and if they have complications. No …