COLO-RECTAL CANCER

This study tests a new drug called MBRC-201 in people with advanced solid tumors (like prostate, breast, lung, colorectal, or pancreatic cancer) that have not responded to standard therapies. The drug is an antibody-drug conjugate, designed to deliver a cancer-killing agent direc…

This early-phase study tests a new drug called ALX2004 in people with advanced lung, head and neck, colorectal, or esophageal cancers that have stopped responding to standard treatments. ALX2004 is an antibody-drug conjugate designed to deliver a toxic payload directly to cancer …

This study tests whether artificial intelligence (AI) can help surgeons better predict risks for people having surgery for colorectal cancer. About 1,200 patients across Denmark will be split into two groups: one where the surgeon uses standard methods to assess risk, and another…

This study looks at whether treating small numbers of cancer spread (1 to 10 spots) right away helps people live longer compared to waiting six months. It includes adults with lung, colorectal, or prostate cancer that has newly spread. The goal is to see if immediate treatment im…

This study is testing how well the Shield blood test works when used a second time to screen for colorectal cancer and advanced polyps. It will include about 3,375 people aged 45 to 81 who are at average risk and plan to have the Shield test as part of their routine care. The res…

This study is testing a blood test (called a liquid biopsy) to see if it can find colorectal cancer, precancerous polyps, and Lynch syndrome-related cancers early. Researchers will collect blood from 1,200 people who have already had a colonoscopy and see how accurate the test is…

This study is testing a new blood test (Natera CRC Screening Test) to see how well it can detect colorectal cancer and advanced growths in people at average risk. About 25,000 adults aged 40 and older who are already scheduled for a colonoscopy will provide blood samples. The tes…

This study tests whether a special training program can help people with a permanent colostomy feel more confident in managing their stoma and daily life. Researchers will enroll 70 adults who have had colorectal surgery. The program focuses on education and support to improve se…

This pilot study works with staff at community health centers to find better ways to increase colorectal cancer screening. Researchers will hold group discussions and analyze health records to see what strategies work best. The goal is to make it easier for people to get screened…

This study tests whether a new app with animations and games helps people prepare for a colonoscopy better than the usual paper instructions. About 252 adults will be randomly assigned to one of two education methods. The goal is to see which approach leads to cleaner bowels, hig…

This study is testing a new single-port robotic system for colorectal surgeries, such as for cancer or rectal prolapse. It involves 25 adults and aims to see if the robot is safe and effective compared to current multi-port robots. The focus is on measuring complications and reco…

This study is building a platform to better predict who is at risk for developing or having a recurrence of certain cancers, including breast, colon, ovarian, melanoma, and lung cancer. Researchers will analyze participants' blood and genetic information to find markers that coul…