COLITIS

This study tests whether long-acting antibodies can help people with moderate to severe ulcerative colitis (UC). About 645 adults will receive the antibodies through an IV and then as shots under the skin. The goal is to see if these treatments reduce gut inflammation and lead to…

This early-phase study tests whether fecal microbiota transplantation (FMT) can safely reduce diarrhea and colon inflammation caused by immune-checkpoint inhibitors in people with genitourinary and other cancers. About 40 participants will receive FMT and be monitored for side ef…

This study tests if fecal microbiota transplantation (FMT) can help people with diarrhea and colitis caused by immune checkpoint inhibitors, a type of cancer immunotherapy. About 20 adults with melanoma or kidney cancer will receive either FMT capsules or placebo capsules alongsi…

This early-stage study tests a drug called KAN-004 in 21 adults who have diarrhea or colon inflammation from cancer immunotherapy. The main goal is to see if the drug is safe and tolerable. Participants must have a solid tumor and be able to swallow capsules.

This study looks at how the bacteria in your gut might influence stomach issues like diarrhea and colitis caused by certain cancer drugs (immune checkpoint inhibitors). Researchers will collect stool, blood, and tissue samples from 800 people with melanoma, lung cancer, or genito…