CLINICAL STAGE IV CUTANEOUS MELANOMA AJCC V8
Clinical trials for CLINICAL STAGE IV CUTANEOUS MELANOMA AJCC V8 explained in plain language.
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Experimental cocktail aims to reboot immune attack on tough cancers
Disease control TerminatedThis early-phase study tested a drug called plinabulin combined with radiation and immunotherapy in 19 people with advanced cancers (like lung, bladder, or melanoma) that had stopped responding to standard immunotherapy. The goal was to see if the combination was safe and could s…
Matched conditions: CLINICAL STAGE IV CUTANEOUS MELANOMA AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 05:16 UTC
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Modified virus targets Hard-to-Treat melanoma in early trial
Disease control TerminatedThis early-phase trial tested a specially modified virus (VSV-IFNb-TYRP1) in 12 people with advanced melanoma that had spread or couldn't be removed. The virus was injected directly into tumors and into a vein to see if it could safely trigger the immune system to attack cancer c…
Matched conditions: CLINICAL STAGE IV CUTANEOUS MELANOMA AJCC V8
Phase: PHASE1 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 26, 2026 04:38 UTC
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Melanoma study halted early: could a malaria drug help cancer treatment?
Disease control TerminatedThis study looked at adding hydroxychloroquine (a malaria drug) to standard targeted therapy (dabrafenib and trametinib) for people with advanced BRAF V600E/K melanoma that had high LDH levels. The goal was to see if the combination could delay cancer growth. Only 5 people enroll…
Matched conditions: CLINICAL STAGE IV CUTANEOUS MELANOMA AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated May 20, 2026 11:53 UTC
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Cancer brain metastasis drug combo trial halted early
Disease control TerminatedThis study tested two drugs, bintrafusp alfa and pimasertib, in people whose cancer had spread to the brain. The goal was to find the best dose and see if the combination could slow or stop tumor growth. The trial was stopped early after enrolling only 8 participants, so no clear…
Matched conditions: CLINICAL STAGE IV CUTANEOUS MELANOMA AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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Promising combo for brain metastases trial halted after just one patient
Symptom relief TerminatedThis early-stage trial aimed to see if adding a device that sends gentle electric fields (tumor treating fields) to standard radiation and immunotherapy could help people with melanoma that spread to the brain. Only one person took part before the study was stopped early. The mai…
Matched conditions: CLINICAL STAGE IV CUTANEOUS MELANOMA AJCC V8
Phase: PHASE1 • Sponsor: Emory University • Aim: Symptom relief
Last updated May 20, 2026 12:08 UTC