Cleft lip and palate
Clinical trials for Cleft lip and palate explained in plain language.
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Cheaper, less painful bone graft for cleft patients under study
Disease control Recruiting nowThis study compares two bone grafting techniques for people with cleft lip and palate. One method uses a lab-made bone material, while the other uses the patient's own hip bone. The goal is to see which approach is more cost-effective, causes less pain, and heals just as well. Ab…
Matched conditions: CLEFT LIP AND PALATE
Phase 4 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Can a simple painkiller boost drinking after palate repair?
Symptom relief Recruiting nowThis study tests whether adding a pain medicine called Ketorolac to standard care helps children drink more fluids after cleft palate surgery. About 74 children with cleft palate (with or without cleft lip) will take part. The goal is to see if better pain control leads to improv…
Matched conditions: CLEFT LIP AND PALATE
Phase 4 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Which sedative works best for kids after cleft surgery? new study aims to find out
Symptom relief Recruiting nowThis study compares three different sedatives (ketamine, nalbuphine, and dexmedetomidine) given to 60 children aged 6 months to 3 years who need stitches removed after cleft lip or palate surgery. The goal is to see which drug works fastest and safest to keep the child calm and c…
Matched conditions: CLEFT LIP AND PALATE
Sponsor: University Medical Centre Ljubljana • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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3D-Printed shield could prevent mouth injuries during cleft surgery
Symptom relief Recruiting nowThis study tests a custom 3D-printed silicone tray that covers the cleft during intubation (placing a breathing tube) in children with cleft lip and palate. The goal is to reduce injuries like bleeding or swelling and make the procedure safer. About 120 children will take part, a…
Matched conditions: CLEFT LIP AND PALATE
Sponsor: Brno University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Can the pace of speech therapy make a difference for kids with cleft palate?
Knowledge-focused Recruiting nowThis study investigates how children with cleft palate, their parents, and speech-language pathologists perceive high-intensity versus low-intensity speech therapy. High-intensity therapy involves five 30-minute sessions per week over two 2-week periods, while low-intensity thera…
Matched conditions: CLEFT LIP AND PALATE
Sponsor: University Ghent • Aim: Knowledge-focused
Last updated Aug 26, 2026 00:00 UTC
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Scientists hunt for hidden genes behind cleft lip and palate
Knowledge-focused Recruiting nowThis study aims to find genetic factors that may cause cleft lip and palate. Researchers will analyze the DNA of 30 people with the condition using advanced sequencing. The goal is to better understand the genetic roots of this birth defect, which could inform future research.
Matched conditions: CLEFT LIP AND PALATE
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC