Cleft lip and palate
Clinical trials for Cleft lip and palate explained in plain language.
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New putty could replace painful bone grafts for kids with cleft palate
Disease control CompletedThis study tested a new calcium phosphate putty to repair bone gaps in the gums of 84 children with unilateral cleft lip and palate. The putty was compared to the standard approach of using the child's own bone. Researchers measured how much bone remained after one year, as well …
Matched conditions: CLEFT LIP AND PALATE
Sponsor: UMC Utrecht • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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New jaw expander could improve smiles for kids with cleft lip and palate
Disease control CompletedThis study tested a new device called the Leaf Self Expander to widen the upper jaw in 20 children with cleft lip and palate. The device was compared to the standard rapid maxillary expander. Researchers used 3D scans to measure changes in bone and tooth position. The goal was to…
Matched conditions: CLEFT LIP AND PALATE
Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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Can a nerve block Add-On calm pain and agitation after cleft palate repair?
Symptom relief CompletedThis trial tests whether adding nalbuphine to a standard numbing medicine improves pain control and reduces agitation in children aged 1 to 7 after cleft palate repair. Half of the 60 participants receive the standard nerve block with bupivacaine alone, while the other half recei…
Matched conditions: CLEFT LIP AND PALATE
Phase 2/3 • Sponsor: Assiut University • Aim: Symptom relief
Last updated Sep 03, 2026 00:00 UTC
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Could a phone app help parents of kids with special needs thrive?
Symptom relief CompletedThis trial tests a 12-week smartphone-based program called PACT, which combines acceptance and commitment training with positive parenting advice, for parents of children with special health care needs. The goal is to see if it can improve parents' mental well-being, psychologica…
Matched conditions: CLEFT LIP AND PALATE
Sponsor: Chinese University of Hong Kong • Aim: Symptom relief
Last updated Aug 13, 2026 00:00 UTC
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Baby teeth stem cells may spare kids a second surgery for cleft palate repair
Symptom relief CompletedThis trial tests whether stem cells from children's shed baby teeth can replace the standard hip bone graft for repairing a cleft in the upper jaw. Twenty children aged 7 to 12 with cleft lip and palate will receive either the stem cell graft or a traditional bone graft from thei…
Matched conditions: CLEFT LIP AND PALATE
Phase 1/2 • Sponsor: Hospital Sirio-Libanes • Aim: Symptom relief
Last updated Jul 31, 2026 00:00 UTC
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Could a simple questionnaire unlock the secrets of Kids' eating disorders?
Knowledge-focused CompletedThis study tested a new parent questionnaire called ORALQUEST to assess feeding and eating disorders in children aged 9 months to 6 years. Researchers included 338 children with chronic conditions like heart defects or autism, as well as those with picky eating. The goal was to s…
Matched conditions: CLEFT LIP AND PALATE
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Aug 27, 2026 00:00 UTC
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New 3D face scans could help babies with cleft lip
Knowledge-focused CompletedThis study tested a new way to measure nose and lip shape in 14 infants with cleft lip and palate using 3D facial scans. Researchers compared these scans to standard photos and manual measurements to see if the digital method is accurate. The goal is to find a better, less invasi…
Matched conditions: CLEFT LIP AND PALATE
Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Cleft Surgery's hidden impact on palate blood flow revealed
Knowledge-focused CompletedThis study looked at how routine cleft repair surgery changes blood flow in the roof of the mouth. Researchers used a non-invasive probe to measure oxygen levels in the tissue before and after surgery in 77 patients. The goal was to understand the surgery's effect on tissue healt…
Matched conditions: CLEFT LIP AND PALATE
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC