CIRRHOSIS, LIVER

This study tests whether adding a traditional Chinese medicine formula (Fufang Biejiaruangan) to standard antiviral therapy can lower the chance of developing liver cancer in people with hepatitis B-related cirrhosis. About 1,034 high-risk adults (ages 18-65) will be randomly ass…

This study tests whether adding Babao Dan Capsule, a traditional Chinese medicine, to standard antiviral therapy can lower the chance of developing liver cancer in people with hepatitis B-related cirrhosis who are at high risk. About 1,034 participants will be randomly assigned t…

This study tests whether a low dose of the drug erlotinib can prevent liver cancer in 60 adults with advanced liver scarring (fibrosis or cirrhosis). Participants will receive either erlotinib or a placebo for a set period. The main goal is to see if the drug changes a blood test…

This study follows 30 adults with liver cirrhosis who need surgery to treat bleeding from high blood pressure in the liver. Researchers will measure changes in cholesterol and other blood fats before and for 2 years after the surgery. The goal is to learn if the surgery improves …

This study follows 30 adults with liver cirrhosis and a history of bleeding from high blood pressure in the liver. They will have laparoscopic spleen removal and a vein-tying surgery. Researchers will measure kidney function before and for 2 years after surgery to see if the proc…

This study looks at 2,500 adults with liver scarring (cirrhosis) or high blood pressure in the liver (portal hypertension) to find out how often bleeding happens during planned medical procedures. Current blood tests don't predict bleeding well, so researchers will track patients…