CHRONIC RHINOSINUSITIS (DIAGNOSIS)

This study tests whether rinsing the nose with a solution containing xylitol (a natural sugar alcohol) can reduce sinus symptoms in adults with cystic fibrosis who also have chronic sinusitis. About 38 participants will try both xylitol rinses and standard saltwater rinses at dif…

This study looks at whether adding epinephrine to a nerve block behind the cheekbones can lessen bleeding during sinus surgery for people with chronic sinusitis. About 80 adults will take part. The goal is to see if this approach makes the surgery smoother and safer.

This study was designed to see how chronic sinusitis affects the tiny hair-like cells (cilia) that help clear mucus from the nose. Researchers planned to use glowing nano-sticks to measure how well these cells work. The study was withdrawn before any participants were enrolled, s…

This study looks at the bacteria living in the nose and sinuses of people with chronic sinusitis, allergies, or healthy sinuses. Researchers want to find out if certain bacteria trigger inflammation that leads to long-term sinus problems. The goal is to gather basic knowledge tha…

This study looks at why some people get chronic sinusitis with nasal polyps, a condition where the sinuses stay inflamed and growths form. Researchers think changes in how genes work (epigenetics) and certain viruses might be the cause. They will compare tissue samples from 60 pe…