CHRONIC RHINOSINUSITIS (DIAGNOSIS)
Clinical trials for CHRONIC RHINOSINUSITIS (DIAGNOSIS) explained in plain language.
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Could a cystic fibrosis drug ease stubborn sinus infections?
Symptom relief Recruiting nowThis early study tests the drug ivacaftor in 20 adults with chronic sinusitis and gram-negative bacteria that didn't get better with standard treatment. The goal is to see if the drug is safe and can improve sinus symptoms and quality of life. Participants will take the drug for …
Matched conditions: CHRONIC RHINOSINUSITIS (DIAGNOSIS)
Phase: EARLY_PHASE1 • Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated May 26, 2026 08:58 UTC
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Good bacteria rinse may soothe stuffy sinuses
Symptom relief Recruiting nowThis study tests whether rinsing the sinuses with a probiotic solution can reduce symptoms of chronic sinusitis better than a standard saltwater rinse. Researchers will enroll 60 adults who have had sinus surgery in the past. Participants will use the rinse daily and report chang…
Matched conditions: CHRONIC RHINOSINUSITIS (DIAGNOSIS)
Phase: PHASE2 • Sponsor: University of Illinois at Chicago • Aim: Symptom relief
Last updated May 20, 2026 11:54 UTC
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Tiny lab study probes Mepolizumab's effect on sinus cells
Knowledge-focused Recruiting nowThis early-stage lab study uses nasal cells from people with chronic sinusitis and nasal polyps to see how the drug mepolizumab affects inflammation and cell barrier health. The study is small (8 participants) and takes place in a lab, not in patients directly. It aims to underst…
Matched conditions: CHRONIC RHINOSINUSITIS (DIAGNOSIS)
Phase: EARLY_PHASE1 • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated May 26, 2026 09:00 UTC
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Sinus surgery for cystic fibrosis: does it help lungs?
Knowledge-focused Recruiting nowThis study looks at whether sinus surgery improves lung function and quality of life in adults with cystic fibrosis who also have chronic sinusitis. Researchers will compare people who have surgery with those who only receive medical treatment. The goal is to understand the real-…
Matched conditions: CHRONIC RHINOSINUSITIS (DIAGNOSIS)
Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated May 26, 2026 08:35 UTC
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New study tracks sinus health in kids with cystic fibrosis
Knowledge-focused Recruiting nowThis study looks at how modern cystic fibrosis medicines affect sinus disease and sense of smell in children ages 2 to 8. Researchers will use MRI scans, smell tests, and quality-of-life surveys over two years. The goal is to understand if these treatments help improve sinus and …
Matched conditions: CHRONIC RHINOSINUSITIS (DIAGNOSIS)
Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC