CHRONIC LYMPHOCYTIC LEUKEMIA
Clinical trials for CHRONIC LYMPHOCYTIC LEUKEMIA explained in plain language.
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Experimental NK cell cocktail aims to outsmart resistant lymphoma
Disease control Not yet recruitingThis early-phase trial tests a combination of two antibody drugs (rituximab and tafasitamab) plus donated natural killer (NK) immune cells for people with B-cell non-Hodgkin lymphoma that has returned or not responded to at least two prior treatments. Up to 15 participants will r…
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA
Phase: PHASE1 • Sponsor: Paolo Caimi, MD • Aim: Disease control
Last updated May 26, 2026 08:53 UTC
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Leukemia patients may get a break from daily pills
Disease control Not yet recruitingThis study looks at whether people with chronic lymphocytic leukemia (CLL) who have been in remission for at least two years can safely stop taking their BTK inhibitor medication. Researchers will track how long patients stay cancer-free without treatment, and whether quality of …
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA
Phase: PHASE2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated May 26, 2026 08:31 UTC
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New combo aims to outperform standard CLL treatment in older patients
Disease control Not yet recruitingThis phase 3 trial tests whether adding sonrotoclax to zanubrutinib for a fixed time works better than taking zanubrutinib alone long-term in older adults with untreated chronic lymphocytic leukemia or small lymphocytic lymphoma. About 466 participants will be randomly assigned t…
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated May 26, 2026 08:30 UTC
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New drug cocktail aims to outsmart tough blood cancers
Disease control Not yet recruitingThis study tests a new drug, NX-5948, combined with other medicines (venetoclax and possibly rituximab or obinutuzumab) in adults with B-cell cancers such as lymphoma, chronic lymphocytic leukemia, and small lymphocytic lymphoma. The goal is to see if the combination is safe and …
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA
Phase: PHASE1, PHASE2 • Sponsor: Nurix Therapeutics, Inc. • Aim: Disease control
Last updated May 22, 2026 13:55 UTC
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Colombia launches first CAR-T trial for relapsed blood cancers
Disease control Not yet recruitingThis study aims to bring a personalized cell therapy called CAR-T to Colombia for people with certain blood cancers that have come back or not responded to treatment. The therapy involves modifying a patient's own immune cells to attack cancer. The trial will check if it is safe …
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA
Phase: NA • Sponsor: GUSTAVO SALGUERO • Aim: Disease control
Last updated May 19, 2026 11:48 UTC
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New hope for Tough-to-Treat blood cancers: phase 3 trial launches
Disease control Not yet recruitingThis study tests a new drug, NX-5948, against another drug, pirtobrutinib, in people with chronic lymphocytic leukemia or small lymphocytic lymphoma that has returned or stopped responding to prior treatment. About 620 adults whose cancer progressed after a previous BTK inhibitor…
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA
Phase: PHASE3 • Sponsor: Nurix Therapeutics, Inc. • Aim: Disease control
Last updated May 19, 2026 11:48 UTC
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New drug duo aims to wipe out hidden leukemia cells
Disease control Not yet recruitingThis study tests two oral drugs, nemtabrutinib and venetoclax, given together as the first treatment for people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). The goal is to see if the combination can clear even the tiniest traces of cancer from the …
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA
Phase: PHASE2 • Sponsor: Jennifer Woyach • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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New drug cocktail aims to deeply suppress blood cancer
Disease control Not yet recruitingThis study tests a combination of three drugs (acalabrutinib, venetoclax, and tafasitamab) in 35 adults with previously untreated chronic lymphocytic leukemia or small lymphocytic lymphoma. The goal is to see if the combo is safe and can achieve a complete response with undetecta…
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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Are CLL referrals fair? new study investigates
Knowledge-focused Not yet recruitingThis study surveys doctors and nurses to understand how patients with chronic lymphocytic leukemia (CLL) are referred to specialists. The goal is to identify differences in referral practices across the West Midlands region of the UK and find ways to make care more equal. About 1…
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA
Sponsor: The Royal Wolverhampton Hospitals NHS Trust • Aim: Knowledge-focused
Last updated May 26, 2026 08:29 UTC
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New study aims to make allergy testing safer for cancer patients on biologics
Knowledge-focused Not yet recruitingThis study looks at how to safely test for allergic reactions to biotherapy drugs in cancer patients. Researchers will find the highest skin test dose that does not cause irritation in most people. The goal is to create clear guidelines for doctors to diagnose allergies to these …
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA
Phase: NA • Sponsor: University Hospital, Angers • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC