CHRONIC LOW-BACK PAIN (CLBP)

This study looks at whether adding a bone-marrow concentrate injection during routine back surgery can help the spinal disc heal better. About 90 adults with a herniated disc will either get surgery alone or surgery plus the injection. Researchers will use MRI scans and pain ques…

This study looks at whether acupuncture can help people with chronic low back pain caused by myofascial pain syndrome (muscle knots). Sixty-four adults will receive either real or fake (sham) acupuncture for eight weeks. Researchers will use full-body PET/CT scans to see if chang…

This study tests whether using a smartphone app that distracts your attention during exercise helps people with chronic low back pain stick to their workout routine. Researchers will enroll 60 adults with long-term back pain and measure how often they exercise, their pain levels,…

This study looks at whether adding percussive massage therapy (like a massage gun) with a heat attachment to standard rehab can reduce pain and disability in people with chronic low back pain. About 48 adults aged 25-55 with long-term back pain will take part. They will either ge…

This study tests whether a single dose of psilocybin can improve how people with chronic low back pain sense their body, and whether that leads to less pain and better results from physical therapy. About 45 adults aged 18-65 with long-lasting low back pain will take psilocybin a…

This study looks at whether adding a special dry needling technique to standard exercises can reduce pain and improve movement in people with long-term low back pain. About 42 adults with pain near the back of the hip will be split into two groups: one gets needling plus exercise…

This study looks at whether combining electroacupuncture (using tiny electric pulses on needles) with ear acupressure (pressing seeds on ear points) can reduce pain and improve daily function in people with long-term low back pain from worn-out spine joints. About 76 adults aged …

This study tests different exercise programs for adults aged 40 to 60 with long-term low back pain. Over 8 weeks, participants will do supervised strength training or special exercises, some with a device that gives feedback on belly muscle tension. The goal is to see which appro…

This study compares virtual reality (VR) exercises to standard physical therapy for people with chronic low back pain. About 48 adults aged 18-65 will do either VR or regular exercises for 8 weeks. Researchers will measure muscle changes, balance, pain, and satisfaction to see if…

This study tests a new virtual reality (XR) system combined with AI to help people with chronic low back pain stick to their exercise programs. About 314 adults will either use the XR system at home and in the clinic, or receive standard group therapy. The goal is to see if the X…

This study aims to better understand low back pain by closely observing 600 people (300 with acute pain and 300 with chronic pain) over 6 months. Participants will use a smartphone app and a wrist-worn activity tracker to report their pain, movement, and psychological factors lik…

This study tests whether short voice recordings can estimate pain intensity and physical limitations in people with chronic low back pain. Researchers will analyze voice features like pitch and speech rate and compare them to standard pain and disability questionnaires. The goal …