CHONDROSARCOMA

This study tests a drug called AG-120 in 6 adults with a rare bone cancer (chondrosarcoma) that has a specific genetic change (IDH1 mutation). The goal is to see if the drug can stop or slow the cancer from growing. Participants have advanced or recurrent disease that cannot be r…

This early-stage study tests an oral drug called LY3410738 in people with advanced solid tumors that have IDH1 or IDH2 gene mutations, including bile duct cancer, cartilage cancer, and brain tumors. The main goals are to find the best dose and check safety. About 200 participants…

This study tests proton beam therapy, with or without standard radiation, for people with skull base chondrosarcoma, a rare cancer. The goal is to see if this treatment can control tumor growth and prevent recurrence. Fifteen participants who have had surgery will receive this ta…

This early-phase trial tests whether zoledronic acid, a drug used to strengthen bones, can help people with a rare cartilage cancer called chondrosarcoma. About 17 adults with tumors that can be removed by surgery will receive the drug before their operation. The main goals are t…

This study looks back at 77 cases of a rare bone cancer called clear cell chondrosarcoma in Italy. Researchers want to learn more about how the disease behaves and what affects a patient's outlook. By reviewing medical records and images, they hope to create a better way to predi…

This study follows 400 adults who had skull base surgery through the nose. Researchers will measure quality of life and nose function for 2 years after surgery. The goal is to understand how modern surgical techniques affect long-term recovery and daily living.