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Rare bone tumor under the microscope: can we predict its behavior?

NCT ID NCT07360964

Knowledge-focused Sponsor: Istituto Ortopedico Rizzoli Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study gathers information from 77 Italian patients with a rare, low-grade bone tumor called clear cell chondrosarcoma. Researchers will review medical records, imaging, and tissue samples to find patterns that might predict whether the tumor will come back or spread. The goal is to create a model that helps doctors better estimate a patient's outlook, but no new treatments are being tested.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could provide doctors with better tools to predict how this rare bone tumor will behave, helping guide treatment decisions.
What could go wrong
This is an observational study, not a treatment trial. It looks back at past cases, so results may not apply to future patients. The small number of cases (77) limits how much we can learn.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

77 people

The number who actually took part.

Started

Sep 2025

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male and female patients with diagnosis of clear cell chondrosarcoma and chondrosarcoma with a clear cell component treated from 01 Jan 1982 to 31 Dec 2023 * Information available (date of primary tumor diagnosis, local treatments, systemic treatment, response to systemic treatment, date of progression) and date and status at last follow-up * Imaging studies available for revision * Histological slides available for revision Exclusion Criteria: * \- Diagnosis different from clear cell chondrosarcoma or chondrosarcoma with a clear cell component; * Absence of radiological and/or clinical data

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Conditions

The condition(s) this trial relates to.

chondrosarcoma Chondrosarcoma, Clear Cell clear cell chondrosarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chondrosarcoma

Contacts and locations

Locations

  • IRCC Rizzoli Orthopedic Institute

    Bologna, 40136, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.