CHILDHOOD CANCER

This study tests new cancer drugs that are chosen based on the unique genetic makeup of each child's tumor. It is for children, teens, and young adults with advanced solid tumors, brain tumors, or lymphoma that have not responded to standard treatments. The goal is to find the ri…

This study tests a program called CHEF that helps childhood cancer survivors and their families cook and eat healthy foods. The goal is to support heart health after cancer treatment. About 17 children who finished chemotherapy or radiation will take part for 6 months. Researcher…

This study looks at whether a wearable device and a symptom questionnaire can accurately detect autonomic dysfunction (a nerve problem affecting heart rate and other automatic body functions) in survivors of childhood leukemia and lymphoma. About 188 adult survivors will use a bi…

This study tests a computer tool called C-SCAT that helps adolescents and young adults with cancer track and manage their symptoms. About 126 participants will either use the tool or receive usual care. The goal is to see if the tool improves their confidence and ability to manag…

This study tests an online program called PLAY for caregivers of young childhood cancer survivors. The program includes online lessons and video coaching to help parents support their child's school readiness and manage stress. About 105 caregivers will try the program and give f…

This study follows 3,000 childhood cancer survivors in Switzerland to understand long-term health problems caused by past cancer treatments. Researchers collect data from check-ups, lab tests, and questionnaires. The goal is to learn more about late effects so doctors can better …

This study tests a new tool called HPARSS to help doctors identify childhood cancer survivors who are at risk for vision or hearing problems due to their past treatment. The tool links a patient's therapy history to the specific screening tests they need. The goal is to make sure…

This study gathers health data from up to 30,000 children treated for cancer at St. Jude Children's Research Hospital. The goal is to monitor their long-term outcomes and any late side effects from treatment. No new drugs or procedures are tested—just careful observation to impro…

This study collects and freezes testicular tissue from prepubertal boys who are about to receive cancer treatment that has a high risk of causing infertility. The tissue is stored for possible future use to help them have children, and a portion is used for research to better und…

This study aims to find blood markers that show if a child's brain has been injured by cancer treatment. Researchers will collect blood samples from 560 children with brain tumors before and after surgery, radiation, or chemotherapy, and compare them to healthy children. The goal…

This study looks at why survivors of childhood acute lymphoblastic leukemia (ALL) often have weak muscles. Researchers will use MRI scans, ultrasound, and small muscle samples to compare survivors with healthy volunteers. The goal is to learn how cancer and its treatment affect m…