CHILDHOOD CANCER

This study tests two short-term drug combinations (dasatinib plus quercetin, or fisetin alone) in 110 adult survivors of childhood cancer who are frail. The goal is to see if these treatments can reduce signs of cell aging and improve walking speed. The trial is a first step towa…

This study tests a modified chemotherapy plan for children with Down syndrome who are newly diagnosed with acute lymphoblastic leukemia (ALL). The treatment uses lower doses of certain drugs to reduce side effects while still fighting the cancer. About 60 children across Asia are…

This study offers children and teens with cancer a personalized exercise program with a trained professional. The goal is to see if kids stick with the program for 4 to 6 months during their cancer treatment. Researchers will ask children and parents about what motivates them and…

This study was designed to see if adult survivors of childhood cancer could successfully use a remote monitoring program at home. Participants would have used wearable devices, answered surveys, and done lab tests to track their heart and metabolic health over 12 weeks. The study…

This study is for children and teenagers who had proton beam therapy for head and neck cancer. Researchers want to learn how this treatment affects the teeth and jaw growth over time. Participants will fill out surveys and some may have interviews and dental check-ups. The goal i…

This study looks at whether data from smartphones and wearable devices can help predict future health problems in adults who survived childhood cancer. About 600 survivors will track symptoms, activity, sleep, and heart rate. The goal is to use this information to improve follow-…

This study aimed to use wearable fitness trackers and smartphone apps to measure heart rate and sleep patterns in adult survivors of childhood cancer. Researchers wanted to compare these measures with healthy siblings to understand if survivors have a higher risk of heart-related…

This study looks at how cancer changes the social lives of teenagers and young adults, both during and after treatment. Researchers will interview about 120 participants aged 15-22 to understand their friendships, feelings of loneliness, and need for social support. The goal is t…

This study gathers feedback from childhood cancer survivors aged 18-39 to improve exercise videos originally made for older adults. The goal is to make the videos more relatable and useful for survivors who are not very active. About 10 participants will share their opinions thro…

This study follows young adult men who had strong chemotherapy or radiation as children for cancer or blood disorders. Researchers want to see how these treatments affected their ability to have children, and whether storing a small piece of testicular tissue before treatment hel…

This study aimed to find early warning signs of heart damage in children receiving chemotherapy for cancer. Researchers planned to use heart scans and genetic tests to identify which children were most at risk. However, the study was withdrawn before enrolling any participants, s…

This study looks at whether a daily mindfulness app can help adult survivors of childhood leukemia or lymphoma cope with stress. About 50 participants will use the app for 30 days and wear a wrist device to track stress signs. The goal is to see if this approach is practical and …

This study looks at whether a smartwatch ECG can work as well as a standard hospital ECG to predict a heart condition called cardiomyopathy in adults who survived childhood cancer. About 1,300 survivors will have both types of ECGs taken during one visit. The goal is to see if th…