Charcot-Marie-Tooth disease
Clinical trials for Charcot-Marie-Tooth disease explained in plain language.
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New fabric brace could give arm strength back to patients with muscle diseases
Symptom relief CompletedThis study tests a special fabric shoulder brace designed to mimic muscle support for people with neuromuscular disorders like muscular dystrophy, SMA, and ALS. About 30 participants will wear the brace and perform arm tasks to see if it improves movement, strength, and daily fun…
Matched conditions: CHARCOT-MARIE-TOOTH DISEASE
Sponsor: Seoul National University Hospital • Aim: Symptom relief
Last updated Sep 05, 2026 00:00 UTC
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Could a simple device ease nerve pain in Charcot-Marie-Tooth?
Symptom relief CompletedThis study tested whether a TENS device, which sends mild electrical pulses through the skin, can reduce leg pain in people with Charcot-Marie-Tooth disease. Ten adults with chronic pain participated. The goal was to see if pain scores dropped by at least 30%.
Matched conditions: CHARCOT-MARIE-TOOTH DISEASE
Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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New drug shows promise for nerve disease that affects walking
Symptom relief CompletedThis study tested a new medicine called NMD670 in 81 adults with Charcot-Marie-Tooth disease types 1 and 2. Participants took either the drug or a placebo twice daily for 21 days. The main goal was to see if the drug could improve walking distance in 6 minutes. The study also che…
Matched conditions: CHARCOT-MARIE-TOOTH DISEASE
Phase 2 • Sponsor: NMD Pharma A/S • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Tiny study probes muscle oxygen in rare nerve and muscle diseases
Knowledge-focused CompletedThis completed study looked at how muscle oxygen levels change during exercise in people with various neuromuscular diseases compared to healthy volunteers. Seventeen participants did a knee-extension exercise while a device measured muscle oxygen. The goal was to understand diff…
Matched conditions: CHARCOT-MARIE-TOOTH DISEASE
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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New scale aims to better track nerve disease in kids
Knowledge-focused CompletedThis study created and tested a new scale called the CMT Pediatric Scale to measure symptoms and physical function in children with Charcot-Marie-Tooth disease. Researchers enrolled 500 children under 21 with CMT types 1, 2, or 4 at multiple centers. The scale assesses foot and h…
Matched conditions: CHARCOT-MARIE-TOOTH DISEASE
Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC