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Could a simple device ease nerve pain in Charcot-Marie-Tooth?

NCT ID NCT01918826

Symptom relief Sponsor: Centre Hospitalier Universitaire de Nice Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a TENS device, which sends mild electrical pulses through the skin, can reduce leg pain in people with Charcot-Marie-Tooth disease. Ten adults with chronic pain participated. The goal was to see if pain scores dropped by at least 30%.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
TENS (transcutaneous electrical nerve stimulation) device
What this could lead to
If it works, this could offer a drug-free, low-risk way to manage chronic pain in Charcot-Marie-Tooth disease.
What could go wrong
This is a very small, early study with only 10 participants, so results may not apply to everyone. Pain relief may be minimal or not last.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

10 people

The number who actually took part.

Started

Aug 2012

Finished

Jul 2014

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age included between 18 and 75 years * Affected by CMT confirmed on clinical, family criteria, electrophysiological and / or genetics * pain ≥ 3 months * EVA pain ≥ 4/10 * patient having given his written consent and lit(enlightened) * patient susceptible to be followed regularly during at least 3 months * Patient member to the Social Security Exclusion Criteria: * Expanding patients of associated neurological pathology * Patients having resorted to the TENS in the last 3 months * Medical history of cancers, collagen and quite other pathology which can interfere with the experimental procedure * Patient carrier of a pacemaker or an active implantable medical device * Cutaneous hurt on the territory to be stimulated * Venous or arterial thrombosis or thrombophlebitis in the territory to be stimulated * Patient participant in another biomedical research on the pain or the period of exclusion of which in a study is not ended * Patient under guardianship or deprived of all his liberties

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Conditions

The condition(s) this trial relates to.

Charcot-Marie-Tooth disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Charcot-Marie-Tooth disease

Contacts and locations

Locations

  • CHU de Nice

    Nice, 06000, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.