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Tiny study probes muscle oxygen in rare nerve and muscle diseases

NCT ID NCT02789059

Knowledge-focused Sponsor: University Hospital, Lille Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at how muscle oxygen levels change during exercise in people with various neuromuscular diseases compared to healthy volunteers. Seventeen participants did a knee-extension exercise while a device measured muscle oxygen. The goal was to understand differences in muscle oxygen use, especially in diseases linked to a missing protein called dystrophin. Some participants also had a muscle biopsy to study mitochondria, the cell's energy factories.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

17 people

The number who actually took part.

Started

Jul 2015

Finished

Dec 2017

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * healthy subjects and * subjects affected by one of the fallowing neuromuscular diseases: Becker Muscular dystrophy Facioscapulohumeral dystrophy, Limb Girdle Muscular Dystrophy , Congenital Myopathy , Spinal Muscular Atrophy Charcot Marie Tooth Disease and Amyotrophic Lateral Sclerosis , * able to walk * presenting a manual muscle testing of at Least 4/5 on the quadriceps according to the Medical research Council Exclusion Criteria: * musculoskeletal pain of the quadriceps * other neurological disorders * Heart failure arrhythmia, uncontrolled hypertension, angina pectoris * dyspnoea \>2 according to the NYHA * Peripheral artery disease * BMI \>30kg.m-2.

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Conditions

The condition(s) this trial relates to.

amyotrophic lateral sclerosis Becker muscular dystrophy Charcot-Marie-Tooth disease congenital myopathy Duchenne muscular dystrophy facioscapulohumeral muscular dystrophy limb-girdle muscular dystrophy neuromuscular disease spinal muscular atrophy Thomsen and Becker disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Neuromuscular diseases

Contacts and locations

Locations

  • CHRU de Lille, Hôpital Swyngedhauw

    Lille, France

  • Hôpital Amiens Nord, Service de Neurologie

    Amiens, France

  • Hôpital Sébastopol, CHU de Reims

    Reims, France

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