CARDIOVASCULAR DISEASES (CVD)

This study is testing a new device called the BrioVAD, a mechanical heart pump for people with advanced heart failure that no longer responds to standard treatments. The goal is to see if the pump is safe and helps patients live longer and feel better. About 60 adults with severe…

This study tests whether taking a prebiotic fiber supplement (WellBiome) for 6-8 weeks before heart surgery can improve recovery. Researchers will measure time in the ICU, complications, and hospital stay in 80 adults aged 50-80. The goal is to see if improving gut health before …

This study tests a new device called the VDyne System to replace the tricuspid valve in people with severe leakage that causes symptoms like shortness of breath and fatigue. About 730 adults who still have symptoms despite medication will be enrolled. The goal is to see if the de…

This study looks at how artificial sweeteners (saccharin, sucralose) and a natural one (erythritol) affect blood sugar control, blood clotting, and heart disease risk in 80 adults with prediabetes. Participants will be assigned to one of four groups and consume a sweetener or wat…

This study looks at whether the supplement quercetin can improve how small blood vessels function in people with obesity. Forty adults aged 18-40 with a BMI over 30 will take quercetin and have their blood vessel health measured using cameras and small sensors placed on the skin.…

This study will use advanced PET scans to measure blood flow and energy use in the brain and body at the same time. Researchers want to see how these responses differ between healthy adults and people with heart disease, especially during mental or physical stress. The goal is to…

This study will collect heart sound recordings from 1,000 adults undergoing routine echocardiograms. Researchers will test whether artificial intelligence (AI) can accurately detect pulmonary hypertension and other cardiovascular diseases from these recordings. The goal is to val…

This study tests a new way to collect health data for heart disease prevention. Researchers want to see if 450 adults will voluntarily share information from their wearable devices (like smartwatches) and health apps. The goal is to make heart health research more inclusive by in…