CARDIOTOXICITY

This study looks at whether cancer survivors who had temporary heart damage from chemotherapy can safely stop taking heart failure medications once their heart function has recovered. About 335 adults who finished cancer treatment at least 6 months ago and are currently on heart …

This study tests whether using a high-efficiency air filter in the bedroom overnight can reduce inflammation in adult cancer survivors who have high levels of a blood marker called C-reactive protein (CRP). Ten participants in Valencia, Spain, will alternate between a real filter…

This study tests a 6-month program of supervised exercise, heart risk management, and online support for young cancer survivors (ages 18-45) who have mild heart dysfunction after cancer treatment. The goal is to see if this program improves fitness, heart function, and quality of…

This study tests whether aggressively lowering blood pressure during breast cancer treatment is safer and more effective than standard care at preventing heart damage. About 130 women with breast cancer and high blood pressure will be assigned to either intensive or standard bloo…

This study tests whether empagliflozin, a drug used for diabetes, can prevent heart damage in cancer patients receiving strong chemotherapy (anthracyclines). About 220 adults with cancer but no prior heart failure will take either empagliflozin or a placebo daily for 12 months. T…

This study looks at whether a 12-week exercise program can improve heart and muscle function in women over 60 who had chemotherapy for breast cancer. Chemo can weaken the heart and reduce physical ability, but exercise might help. Researchers will compare a structured exercise pr…

This study aims to create a computer-based tool that predicts which cancer patients are at risk of heart damage from certain chemotherapy drugs. Researchers will follow 600 patients in France for one year, collecting data to train a machine learning model. The goal is to help doc…

This study is a worldwide registry that will follow 5,000 adults with breast cancer, blood cancers, or those on certain immune therapies. Its goal is to collect data on patients' health, treatments, and heart events to better understand and predict heart problems caused by cancer…

This study looks at people with HER2+ breast cancer that has spread. All are taking trastuzumab, a targeted therapy. The main goal is to track how often heart problems occur. A smaller part of the study tests if the heart drug carvedilol can prevent these side effects.

This study tests whether special MRI scans can find early signs of heart damage in people getting anthracycline chemotherapy, which is known to sometimes harm the heart. Current tests like blood markers and echocardiograms often miss early damage. About 93 adults starting this ty…

This study aims to see if advanced imaging techniques, like special ultrasound and MRI, can find heart damage earlier in children, teens, and young adults who have had cancer treatment. Researchers will follow 400 participants to track heart problems that may appear during or aft…