CARDIOTOXICITY

This study looks at whether different levels of exercise can help the hearts of young adults who survived childhood cancer and were treated with a type of chemotherapy called anthracyclines. About 20 survivors aged 18-39 will take part. The goal is to see if exercise can reduce h…

This study follows 200 women with breast cancer who are receiving doxorubicin and/or trastuzumab to see how these drugs affect heart function over time. Researchers will use echocardiograms, blood tests, and surveys to track changes and explore links to medical history and social…

This study follows 221 people with stage II or III lung cancer to see how chemoradiation therapy affects their hearts. Participants get heart scans and blood tests before, during, and for two years after treatment. The goal is to better understand and track heart damage caused by…

This study looks at whether a cardiopulmonary exercise test (CPET) can help predict heart and lung function in women with HER2-positive breast cancer who have mild heart problems from their treatment. About 23 women will do a special exercise test to measure oxygen use. The goal …

This study looks at how immune checkpoint inhibitors, a type of immunotherapy for cancer, affect the tiny blood vessels in the heart. Researchers will use heart scans and blood tests in 25 adults with breast or lung cancer before and during treatment. The goal is to understand if…

This study watches 200 men with prostate cancer who are getting hormone therapy (androgen deprivation therapy) to see how it affects their heart health. Researchers will use heart ultrasounds, blood tests, and surveys to track changes and look at how factors like race, income, an…

This study watches 50 adults with chronic lymphocytic leukemia who are starting certain drugs (acalabrutinib or zanabrutinib). These drugs can cause high blood pressure and irregular heartbeats. Participants will use wearable devices at home to track their heart rhythm and blood …

This study tests if a wearable sensor can accurately estimate the heart's pumping ability (LVEF) in 50 adults who are already scheduled for an echocardiogram. The goal is to see if the sensor matches the standard ultrasound test. If successful, this could lead to easier, more fre…