CARDIOMYOPATHY

This early-stage study tests whether donor bone marrow stem cells can help control heart failure in people whose hearts were weakened by a type of chemotherapy called anthracyclines. About 72 adults with low heart function will receive either standard care alone or standard care …

This study looks at how well a drug called mavacamten works for adults in Japan who have a heart condition called obstructive hypertrophic cardiomyopathy (HOCM) and are already taking another drug, cibenzoline. The goal is to see if mavacamten helps improve blood flow from the he…

This study looks at whether exercising in a community or home setting can improve exercise capacity in adults aged 18 to 85 with reduced heart or lung function. Two hundred participants will either do supervised exercise (like brisk walking or cycling) five times a week for eight…

This study is testing a new paddle-shaped catheter designed to map the heart's electrical signals in people with various heart rhythm disorders, such as atrial fibrillation and ventricular tachycardia. The goal is to see if the catheter is safe and can successfully map the heart …

This study checks if two different tablet forms of HRS-1893 are processed the same way in the body. It involves 36 healthy adults aged 18 to 55. The goal is to measure drug levels in the blood and monitor safety, not to treat any disease.

This study aims to learn more about heart and blood vessel diseases by observing people who have them or are at risk. Researchers will collect samples and perform tests like heart scans and exercise tests. The goal is to improve diagnosis and understanding of these conditions. An…

This study aims to find the genes that cause inherited heart and muscle diseases like cardiomyopathy, arrhythmia, and muscular dystrophy. Researchers will collect blood or tissue samples from patients and their families to look for genetic mutations. The study does not offer trea…

This study is for breast cancer patients getting certain chemotherapies that can harm the heart. Researchers want to see if a gene called TRPC6 can help predict who might develop heart problems. By studying blood samples from 200 patients, they hope to find early warning signs an…

This study aims to understand how different genetic changes in the DMD gene are linked to heart problems in boys and young men (ages 2-24) with Duchenne or Becker muscular dystrophy. Researchers will use heart tests and blood samples to find early signs of heart issues. The study…

This study watches how heart disease develops and changes over time in 65 people with Friedreich ataxia, a rare genetic condition. Participants must be at least 6 years old and have a thickened heart muscle. The goal is to learn more about the disease, not to test a new treatment…