CARDIOGENIC SHOCK

This early-stage trial tests a new treatment made from donor cells (CAR-DC) for people who have had a severe heart attack and are in shock. The goal is to see if it is safe and can help the heart recover. The study will include 18 adults who have already had emergency heart proce…

This study looks at 500 adults with severe heart failure or shock who need a mechanical heart pump placed through the leg artery. Researchers want to see if routinely placing an extra leg catheter to keep blood flowing is better than only placing it when problems arise. The goal …

This study tests whether a heart pump (Impella 5.5) combined with optimized heart failure medications can help people with severe heart failure and shock recover without needing a transplant or permanent heart assist device. About 250 adults aged 18-79 with a weak heart pump (LVE…

This study tests if a 7-day course of steroids can reduce dangerous inflammation in 30 adults with heart failure-related cardiogenic shock. Participants must have high inflammation levels and be on temporary heart pumps. The goal is to see if steroids safely help the heart and or…

This study reviews medical records of 100 adults who needed a breathing machine after a heart attack or cardiac arrest. Researchers want to see how often acid-base problems occur and compare doctors' ventilator settings with a computer algorithm's suggestions. No new treatments a…

This study aims to see if a standard pressure measurement (PCWP) used during heart surgery matches the most accurate method (LAP). About 136 adults having elective heart surgery will be monitored. The goal is to improve how doctors track heart function and make treatment decision…

This study looks at a new device that can measure a substance called nucleosomes in the blood right at the patient's bedside. Researchers want to see if these levels can help predict which critically ill patients will survive for 30 days. The study will include 130 adults in the …

This study will collect information from 1,200 patients in the French West Indies and Guiana who have received ECMO, a machine that helps the heart and lungs work. The goal is to understand how these patients fare, including survival rates and complications. No new treatments or …

This study is a registry that will collect information from about 320 people in Hong Kong who have had a severe heart attack complicated by cardiogenic shock, a condition where the heart cannot pump enough blood. The goal is to track outcomes for patients who receive a mechanical…