BRONCHIECTASIS

This study aims to test the safety and tolerability of a new inhaled drug called CHF6333 for people with bronchiectasis, a chronic lung disease. It will involve healthy volunteers and people with the condition, testing single and repeated doses. The main goal is to see how the bo…

This Mayo Clinic study is testing whether itraconazole, an antifungal medication, is a practical and safe treatment option for adults with bronchiectasis who also have mold growing in their airways. The small pilot trial with 30 participants will check if patients can stick with …

This study is testing a home breathing therapy device called BiWaze Clear for people with bronchiectasis, a chronic lung condition. Over 6 months, researchers will see if using this device helps reduce the frequency of serious lung infections (exacerbations) and improves patients…

This large, late-stage study is testing whether a daily pill called BI 1291583 can reduce the frequency of painful flare-ups in people with bronchiectasis, a chronic lung condition. About 1,755 participants aged 12 and up who experience these flare-ups will be randomly assigned t…

This study is testing a new smartphone app called AWARE that uses your phone's microphone and speakers to listen to your breathing. The goal is to see if it can accurately help doctors diagnose lung diseases like asthma and COPD, and spot when symptoms are getting worse. Research…

This study is testing a home-based exercise program designed to strengthen breathing muscles and improve core stability in adults with bronchiectasis, a chronic lung condition. Researchers want to see if this specific training, added to standard chest physiotherapy, can improve l…

This study is testing a new digital game and device designed to help children with bronchiectasis perform their daily breathing exercises at home. The game aims to make the repetitive airway clearance therapy more fun and engaging, potentially improving how well kids stick to the…

This study is testing whether a handheld breathing device called an OPEP can improve the day-to-day quality of life for people with bronchiectasis, a chronic lung condition. It will involve 60 children (aged 8+) and adults who are not currently using this type of device. Research…

This study aims to better understand different patterns in chronic lung diseases like asthma, COPD, and cystic fibrosis. Researchers will observe 470 adult patients over 10 years, collecting health data during their regular doctor visits. The goal is to identify shared disease fe…

This study aims to understand how a specific bacterial lung infection (NTM-PD) affects people's health compared to those with a similar lung condition (bronchiectasis) without the infection. Researchers will compare 40 people with each condition using questionnaires and simple ph…

This study aims to understand the link between a person's nutritional status and the progression of bronchiectasis, a chronic lung disease. Researchers will enroll 300 adults with bronchiectasis and measure various nutrition and body composition indicators, then follow them for t…

This study aims to learn more about bronchiectasis, a lung condition that causes repeated infections and breathing problems. Researchers will follow 900 patients and some of their family members over time, collecting health information and samples like blood and sputum. The goal …

This study aims to understand how and why long-term, low-dose antibiotic treatment helps some people with bronchiectasis, a chronic lung disease. Researchers will follow 150 adult patients for two years, collecting sputum, stool, and blood samples to analyze their microbes and bo…

This study aims to understand how bacteria in the lungs of people with bronchiectasis change over time. Researchers will collect sputum samples from 1850 patients every month for three years to analyze these bacteria. The goal is to learn if changes in these bacteria can predict …

This study aims to understand how the community of bacteria in the lungs might be linked to a chronic lung infection called NTM. Researchers will compare samples from 200 people with lung symptoms, some with the NTM infection and some without. The goal is to identify specific bac…

This study aims to understand how exposure to environmental fungi affects people with asthma, allergic bronchopulmonary aspergillosis (ABPA), and bronchiectasis. Researchers will observe 125 participants, including healthy people, for 6 months. They will collect dust samples from…