BRCA1 MUTATION
Clinical trials for BRCA1 MUTATION explained in plain language.
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New Three-Drug cocktail targets BRCA breast cancer
Disease control CompletedThis early-phase trial tested whether combining three drugs—olaparib, palbociclib, and fulvestrant—is safe for people with BRCA-mutated, hormone receptor-positive, HER2-negative metastatic breast cancer. Nine participants received the combination to check for side effects and see…
Matched conditions: BRCA1 MUTATION
Phase: PHASE1 • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Disease control
Last updated Jun 23, 2026 20:49 UTC
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Toolkit helps BRCA carriers tell family about cancer risk
Knowledge-focused CompletedThis study tested whether a 'Disclosure Toolkit' — including a family letter, chatbot, and website — helps people with BRCA gene mutations share their results with at-risk relatives. 52 participants used the toolkit, and researchers measured how many relatives learned about the r…
Matched conditions: BRCA1 MUTATION
Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 23, 2026 20:47 UTC