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Toolkit helps BRCA carriers tell family about cancer risk

NCT ID NCT04428736

First seen Apr 23, 2026 · Last updated Jun 23, 2026 · Updated 10 times

Summary

This study tested whether a 'Disclosure Toolkit' — including a family letter, chatbot, and website — helps people with BRCA gene mutations share their results with at-risk relatives. 52 participants used the toolkit, and researchers measured how many relatives learned about the risk and pursued genetic testing. The goal is to improve family communication and early cancer prevention.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Abramson Cancer Center

    Philadelphia, Pennsylvania, 19104, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Disclosure Toolkit (family letter, chatbot, website)

What this could lead to

If successful, this toolkit could help more at-risk relatives learn about their genetic risks and pursue testing, potentially preventing cancer through early action.

What could go wrong

This is a small, completed study with only 52 participants, so results may not apply to everyone. The toolkit's effectiveness depends on family dynamics and willingness to share.

Conditions

The condition(s) this trial relates to.

BRCA1-related cancer predisposition BRCA2-related cancer predisposition

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.