BRCA MUTATION
Clinical trials for BRCA MUTATION explained in plain language.
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New pill may keep ovarian cancer at bay for longer in BRCA patients
Disease control OngoingThis study tests whether taking olaparib daily after initial chemotherapy can delay cancer growth in people with advanced ovarian cancer who have a BRCA gene mutation. About 450 participants who responded well to first-line platinum chemo will receive either olaparib or a placebo…
Matched conditions: BRCA MUTATION
Phase: PHASE3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated May 26, 2026 03:51 UTC
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New study explores how genetic risk scores shape ovarian cancer decisions
Knowledge-focused OngoingThis study interviews 24 women aged 25 or older who have a BRCA1 or BRCA2 mutation to learn how they might use polygenic risk scores and multi-cancer early detection tests when deciding about cancer screening or risk-reducing surgery. The goal is to better understand women's atti…
Matched conditions: BRCA MUTATION
Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Knowledge-focused
Last updated May 26, 2026 04:03 UTC
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Gene-Targeted prostate screening study aims to uncover cancer risks
Knowledge-focused OngoingThis study looks at whether men with certain inherited gene changes (BRCA1, BRCA2, or mismatch repair genes) have a higher chance of getting prostate cancer. About 3,500 men aged 40-69 with or without these gene changes will get yearly PSA tests. The goal is to learn how often pr…
Matched conditions: BRCA MUTATION
Sponsor: Institute of Cancer Research, United Kingdom • Aim: Knowledge-focused
Last updated May 26, 2026 03:55 UTC
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New database aims to intercept deadly pancreatic cancer before it's too late
Knowledge-focused OngoingThis study is creating a secure database of 317 patients at high risk for pancreatic cancer, including those with cysts, genetic syndromes, or other risk factors. The goal is to find better ways to detect the disease early or even prevent it. No new treatments are being tested; i…
Matched conditions: BRCA MUTATION
Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Knowledge-focused
Last updated May 20, 2026 11:57 UTC