BRCA MUTATION
Clinical trials for BRCA MUTATION explained in plain language.
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New pill combo targets hard-to-treat inherited cancers
Disease control Recruiting nowThis early-stage trial tests a combination of two oral drugs (olaparib and ASTX727) in adults with advanced solid tumors that have specific gene mutations (BRCA1, BRCA2, PALB2, ATM, or CHEK2). The main goals are to find the safest dose and to see if the drugs can shrink tumors. A…
Matched conditions: BRCA MUTATION
Phase: PHASE1 • Sponsor: Pamela Munster • Aim: Disease control
Last updated May 17, 2026 00:43 UTC
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New PARG inhibitor drug trial targets Hard-to-Treat cancers
Disease control Recruiting nowThis study tests a new drug called ETX-19477 in people with advanced solid tumors (like breast, ovarian, or prostate cancer) that have stopped responding to standard treatments. The goal is to find the safest dose and see if the drug can shrink tumors or slow their growth. About …
Matched conditions: BRCA MUTATION
Phase: PHASE1, PHASE2 • Sponsor: 858 Therapeutics, Inc. • Aim: Disease control
Last updated May 11, 2026 20:39 UTC
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Can a simple ultrasound spot cancer risk before it starts?
Diagnosis Recruiting nowThis study aims to see if ultrasound images of healthy ovaries can predict whether a woman carries a harmful BRCA gene mutation, which raises the risk of breast and ovarian cancer. Researchers will develop a computer model using thousands of images from over 6,400 women. If succe…
Matched conditions: BRCA MUTATION
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Diagnosis
Last updated May 17, 2026 00:32 UTC
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New scan may spot hidden prostate cancer spread in men with BRCA and other gene mutations
Diagnosis Recruiting nowThis study aims to see if a type of PET-CT scan called FCH-PET-CT is better than standard scans (bone scan and MRI/CT) at finding cancer that has spread outside the pelvis in men with prostate cancer who have certain inherited gene mutations (like BRCA). About 50 men with these m…
Matched conditions: BRCA MUTATION
Sponsor: Institute of Cancer Research, United Kingdom • Aim: Diagnosis
Last updated May 17, 2026 00:31 UTC