BRCA MUTATION
Clinical trials for BRCA MUTATION explained in plain language.
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New hope to delay ovarian Cancer's return in High-Risk patients
Disease control OngoingThis large, late-stage trial is testing whether a drug called olaparib can help keep advanced ovarian cancer from coming back after initial chemotherapy. It is for women with a specific genetic change (BRCA mutation) whose cancer responded well to first treatment. The study compa…
Matched conditions: BRCA MUTATION
Phase: PHASE3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Researchers ask: how do women weigh new cancer tests against surgery?
Knowledge-focused OngoingThis study aims to understand how women with BRCA gene mutations think about new tools for assessing their ovarian cancer risk. Researchers are interviewing 24 women to learn how they might use genetic risk scores and early detection blood tests when deciding whether to have prev…
Matched conditions: BRCA MUTATION
Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Cancer center hunts for early clues to stop deadly pancreatic tumors
Knowledge-focused OngoingThis study aims to create a large database of patient information to find better ways to detect pancreatic cancer early, when it's most treatable. It involves 317 adults at Moffitt Cancer Center who have pancreatic cysts, a strong family history of pancreatic cancer, or other ris…
Matched conditions: BRCA MUTATION
Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC
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Can early screening save men with 'Cancer Genes'?
Knowledge-focused OngoingThis study aims to understand if annual PSA blood tests can help find prostate cancer earlier in men who carry high-risk BRCA or Lynch syndrome gene mutations. It will compare about 850 men with these mutations to 850 similar men without them over five years. The goal is to learn…
Matched conditions: BRCA MUTATION
Sponsor: Institute of Cancer Research, United Kingdom • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:07 UTC