BRAF GENE MUTATION
Clinical trials for BRAF GENE MUTATION explained in plain language.
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New pill targets hard-to-treat cancers with KRAS and BRAF mutations
Disease control Recruiting nowThis early-stage study tests an oral drug called S241656 in adults with advanced cancers that have certain gene changes (KRAS, BRAF, or related mutations). The drug is given alone or with other cancer treatments. The goal is to find safe doses and see if the drug shrinks tumors. …
Matched conditions: BRAF GENE MUTATION
Phase: PHASE1, PHASE2 • Sponsor: Institut de Recherches Internationales Servier • Aim: Disease control
Last updated May 26, 2026 08:32 UTC
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New combo tackles melanoma that outsmarted standard drugs
Disease control Recruiting nowThis early-phase study tests adding nilotinib to standard targeted therapy for people with advanced melanoma that has a BRAF V600 mutation and has stopped responding to previous BRAF/MEK inhibitor treatment. About 30 participants will receive the drug combination to find the safe…
Matched conditions: BRAF GENE MUTATION
Phase: PHASE1 • Sponsor: Rina Plattner • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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Last-Resort drug made available for patients with tough cancers
Disease control AVAILABLEThis program provides ulixertinib, an experimental drug, to adults with advanced solid tumors that have specific genetic changes (MAPK pathway mutations) and who have run out of standard treatments. The goal is to control the cancer, not cure it. Participants may take ulixertinib…
Matched conditions: BRAF GENE MUTATION
Sponsor: xCures • Aim: Disease control
Last updated May 14, 2026 12:06 UTC