BRAF GENE MUTATION
Clinical trials for BRAF GENE MUTATION explained in plain language.
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Last-Resort drug made available for patients with tough cancers
Disease control AVAILABLEThis program provides ulixertinib, an experimental drug, to adults with advanced solid tumors that have specific genetic changes (MAPK pathway mutations) and who have run out of standard treatments. The goal is to control the cancer, not cure it. Participants may take ulixertinib…
Matched conditions: BRAF GENE MUTATION
Sponsor: xCures • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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New pill targets hard-to-treat cancers with KRAS and BRAF mutations
Disease control Recruiting nowThis early-phase study tests an oral drug called S241656 in adults with advanced cancers that have certain gene changes (KRAS, BRAF, and others). The drug is given alone or with other cancer treatments. The goal is to find safe doses and see if the drug shrinks tumors. About 554 …
Matched conditions: BRAF GENE MUTATION
Phase: PHASE1, PHASE2 • Sponsor: Institut de Recherches Internationales Servier • Aim: Disease control
Last updated May 12, 2026 13:40 UTC
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New hope for Tough-to-Treat skin cancer: trial tests adding a third drug
Disease control Recruiting nowThis early-stage study is testing whether adding a drug called nilotinib to standard melanoma treatments (dabrafenib/trametinib or encorafenib/binimetinib) is safe and tolerable for patients. It is for adults whose advanced, BRAF-mutated melanoma has stopped responding to or prog…
Matched conditions: BRAF GENE MUTATION
Phase: PHASE1 • Sponsor: Rina Plattner • Aim: Disease control
Last updated Apr 13, 2026 20:21 UTC